Holland and Alter published "Non-A, Non-B Viral Hepatitis Human Pathology", which said that "whenever possible, autologous blood and blood products with the lowest risks of hepatitis transmission should be utilized, e.g., the use of single donor plasma or small pools of cryoprecipitated antihemophilic factor in preference to concentrates of clotting factors made from large pools of donors, some of whom are almost certain to be carriers of non-A, non-B hepatitis virus."