Letter from James K. Smith, Acting Head, CF Department, to Dr E. Tuddenham, Royal Free Hospital, re Reject Factor VIII Concentrate for PE Project. Discusses the release of 100 vials of HL2712 and there is a request for provision of a description of the preparative work, an inventory of all product and samples derived from the experiment and a statement of the destination and use of inventoried product. Further discussion on ways of obtaining a concentrate of the required RAgCAg ratio as well as a request that work on this project be published as soon as possible.