NHBT0000047_002 - Blood donor screening to reduce the incidence of transfusion associated NANB hepatitis a history of surrogate marker tests by J Craske - 13 Mar 1998

Report titled Blood donor screening to reduce the incidence of transfusion associated NANB hepatitis a history of surrogate marker tests by Dr John Craske Includes Dr John Craskes conclusions as regards the decision not to introduce surrogate testing Topics discussed are attempts to identify viruses related to transfusion acquired NANB hepatitis early observations of surrogate markers for NANB hepatitis ALT testing the antiHBc test as a surrogate marker of an increased chance of transmitting NANB hepatitis workshop on surrogate testing to reduce the risk of transmitting posttransfusion hepatitis tenth meeting of the Committee of Experts on Blood Transfusion and Immunohaematology of the Council of Europe investigation of the possible use of surrogate markers in blood donor screening in the UK studies by the UK National Blood Transfusion Service to assess whether surrogate marker tests should be used for blood donor screening first generations EIAs for the detection of HCV antibody retrospective studies of the effectiveness of surrogate testing for NANB hepatitis with the development of first generation EIAs for antiHCV antibody