Guidelines for administration of blood products transfusion of infants and neonates. Re discussion of red cell transfusion, treatment of hypovolaemic shock/plasma volume expanders, fresh frozen plasma, platelet therapy, granulocyte therapy, and special hazards of transfusion in neonatal period. Article discusses the relevance of the source of blood for transfusion and the microbiological screening of volunteer donor blood collected in the UK for HBsAg, anti-HCV and anti-HIV.