Letter from Dr Charles RM Hay (in his capacity as Acting Chair of the United Kingdom Haemophilia Centre Doctors Organisation (UKHCDO)) to various recipients including all Haemophilia Centre doctors, Rosemary Spooner (Administrative Secretary of the UKHCDO), Charles Lister of the Department of Health and Karen Pappenheim of the Haemophilia Society. The letter is regarding the shortage of recombinant Factor VIII. The letter provides an outline of why there is a current shortage of Recombinant Factor VIII, how long this is expected to continue, references a guidance document on how to ensure an orderly reduction in the use of recombinant factor VIII; advises of the next meeting of the Advisory Committee and requests further information from all Haemophilia Centres