Freeze-dried fractions made from human blood were developed by Kekwick and Wolf, Soulier, Blombäck and others. Linked evidence RLIT0000022 - Wellcome Witnesses to Twentieth Century Medicine Haemophilia Recent History of Clinical Management - 01 Sep 1999 Chronology Information Date: 1 January 1957 Chapter/issue Blood Products and Addressing Risk: Self-Sufficiency