Letter from S. G. Rainsford, Lord Mayor Treloar College, to D. Guthrie, National Fund for Research Into Crippling Diseases, providing an update on the research programme at Treloars and the four projects underway at Treloars. Project 1: Investigation into seasonal variation in the tendency to bleed; Project 2: Investigation into rheumatoid arthritis in haemophilic joints; Project 3: Abnormal Immunoglobulins and Inhibitors to Factor VIII; Project 4: Investigation into the incidence of Antibody to Australia Antigen in cases of Christmas Disease and Haemophilia.