Dr Rejman observed that "You will recall that in summary the Department feels that there is no justification for routine use of recombinant Factor VIII in patients with haemophilia". Read more about Dr Rejman observed that "You will recall that in summary the Department feels that there is no justification for routine use of recombinant Factor VIII in patients with haemophilia".
Draft briefing for an answer to a parliamentary question which arose in relation to the imposition of VAT on recombinant. Read more about Draft briefing for an answer to a parliamentary question which arose in relation to the imposition of VAT on recombinant.
Dr Savidge stated that market trends in Europe, and North America showed that plasma derived Factor 8 was rapidly being phased out from clinical use in favour of recombinant. Read more about Dr Savidge stated that market trends in Europe, and North America showed that plasma derived Factor 8 was rapidly being phased out from clinical use in favour of recombinant.
Dr Savidge's view on behalf of the Recombinant Factor VIII Users' Group was that the cheaper high purity plasma-derived Factor 8 was substantially contaminated by parvovirus B19. Recombinant Factor 8 was not. Read more about Dr Savidge's view on behalf of the Recombinant Factor VIII Users' Group was that the cheaper high purity plasma-derived Factor 8 was substantially contaminated by parvovirus B19. Recombinant Factor 8 was not.
Dr Savidge did not agree with Kenneth Clarke's comments concerning the comparative safety of the recombinant product. Read more about Dr Savidge did not agree with Kenneth Clarke's comments concerning the comparative safety of the recombinant product.
Dr Rejman wrote: "there is no evidence that recombinant Factor VIII is any safer than plasma derived Factor VIII at the present time. You will be aware that recombinant Factor VIII contains plasma derived albumin as a carrier." Read more about Dr Rejman wrote: "there is no evidence that recombinant Factor VIII is any safer than plasma derived Factor VIII at the present time. You will be aware that recombinant Factor VIII contains plasma derived albumin as a carrier."
Dr Metters made the point that recombinant had a risk, namely, that of being combined with albumin. Read more about Dr Metters made the point that recombinant had a risk, namely, that of being combined with albumin.
Kenneth Clarke stated the treatment of patients with recombinant Factor VIII, which contains human serum albumin as a stabiliser, was not without risk. Read more about Kenneth Clarke stated the treatment of patients with recombinant Factor VIII, which contains human serum albumin as a stabiliser, was not without risk.
Fax from HM Customs and Excise to Dr Rejman regarding Recombinant VAT and Factor VIII. Read more about Fax from HM Customs and Excise to Dr Rejman regarding Recombinant VAT and Factor VIII.
Dr Savidge sent a letter to Kenneth Clarke regarding Recombinant Factor VIII and VAT. Read more about Dr Savidge sent a letter to Kenneth Clarke regarding Recombinant Factor VIII and VAT.