Dr Bowley wrote a letter to colleagues seeking to make a case for using better quality cryoprecipitate instead of imported factor concentrates. Read more about Dr Bowley wrote a letter to colleagues seeking to make a case for using better quality cryoprecipitate instead of imported factor concentrates.
The Expert Group on the Treatment of Haemophilia had set a goal of 250,000 donations to be used for Factor 8 concentrate (March 1973); this had been increased to 275,000 by regional transfusion directors following the Joint Steering Committee (June and July 1973). Read more about The Expert Group on the Treatment of Haemophilia had set a goal of 250,000 donations to be used for Factor 8 concentrate (March 1973); this had been increased to 275,000 by regional transfusion directors following the Joint Steering Committee (June and July 1973).
Dr Lane focused on the view that BPL should be rebuilt. A large investment was required. Read more about Dr Lane focused on the view that BPL should be rebuilt. A large investment was required.
Dr Lane submitted a draft proof of evidence for the HIV Haemophilia Litigation. Read more about Dr Lane submitted a draft proof of evidence for the HIV Haemophilia Litigation.
There was an upward shift in estimates of future needs, though slighter on this occasion. Current demand for Factor 8 was probably in the region of 60 million international units but, if clinical freedom continued, it could reach 100 million international units per annum. Read more about There was an upward shift in estimates of future needs, though slighter on this occasion. Current demand for Factor 8 was probably in the region of 60 million international units but, if clinical freedom continued, it could reach 100 million international units per annum.
A Working Party on Human Antihaemophilic Globulin meeting determined "As the HAHG [human antihaemophilic globulin] concentrate prepared from plasma pools of up to 30-40 litres in volume apparently carried a risk of transmitting serum hepatitis, it was considered inadvisable...to increase the plasma pool volume much above this size". Read more about A Working Party on Human Antihaemophilic Globulin meeting determined "As the HAHG [human antihaemophilic globulin] concentrate prepared from plasma pools of up to 30-40 litres in volume apparently carried a risk of transmitting serum hepatitis, it was considered inadvisable...to increase the plasma pool volume much above this size".
It was apparent that the fractionation capacity in England would need significant expansion. Read more about It was apparent that the fractionation capacity in England would need significant expansion.
At an Association of Haematologists North East Thames Region Working Party in Haemophilia meeting, Dr Lane "projected utilisation of factor VIII concentrate to grow to 60M iu [international units] per annum over a ten-year period" but suggested "100M iu per annum" as a more realistic estimate to achieve self-sufficiency. Read more about At an Association of Haematologists North East Thames Region Working Party in Haemophilia meeting, Dr Lane "projected utilisation of factor VIII concentrate to grow to 60M iu [international units] per annum over a ten-year period" but suggested "100M iu per annum" as a more realistic estimate to achieve self-sufficiency.
The New England Journal of Medicine published an article by Siegal et al titled "Severe Acquired Immunodeficiency in Male Homosexuals, Manifested by Chronic Perianal Ulcerative Herpes Simplex Lesions". Read more about The New England Journal of Medicine published an article by Siegal et al titled "Severe Acquired Immunodeficiency in Male Homosexuals, Manifested by Chronic Perianal Ulcerative Herpes Simplex Lesions".