Dr Craske wrote to the Small Grants Secretariat recording that whilst haemophilia centre directors had agreed in theory to maintaining patients on single batches or brands, the shortage of Factor VIII, large numbers of patients under treatment and the cost of maintaining stocks of Factor VIII meant that they did not consider it to be a practical policy to stick rigidly to this regime. Read more about Dr Craske wrote to the Small Grants Secretariat recording that whilst haemophilia centre directors had agreed in theory to maintaining patients on single batches or brands, the shortage of Factor VIII, large numbers of patients under treatment and the cost of maintaining stocks of Factor VIII meant that they did not consider it to be a practical policy to stick rigidly to this regime.
The reason for the DHSS' suggestion that patients be kept on one type or one batch of concentrate was to simplify analysis and presentation of results, increase the chances of identifying icterogenic material and permit the withdrawal of icterogenic bottles. Read more about The reason for the DHSS' suggestion that patients be kept on one type or one batch of concentrate was to simplify analysis and presentation of results, increase the chances of identifying icterogenic material and permit the withdrawal of icterogenic bottles.
Dr Craske requested haemophilia centre directors send in details of cases of chronic hepatitis on a new form which the Haemophilia Centre Directors' Working Party would draw up and distribute to centres. Read more about Dr Craske requested haemophilia centre directors send in details of cases of chronic hepatitis on a new form which the Haemophilia Centre Directors' Working Party would draw up and distribute to centres.
Haemophilia centre directors agreed in principle that it was a good idea for patients to be kept on one type (or preferably one batch) of concentrate for long periods. Read more about Haemophilia centre directors agreed in principle that it was a good idea for patients to be kept on one type (or preferably one batch) of concentrate for long periods.
In a Haemophilia Centre Directors' Hepatitis Working Party meeting, it was agreed that the NHS Factor 8 associated hepatitis study should start on 1 June 1978. Read more about In a Haemophilia Centre Directors' Hepatitis Working Party meeting, it was agreed that the NHS Factor 8 associated hepatitis study should start on 1 June 1978.
In a Haemophilia Centre Directors' Hepatitis Working Party meeting, Dr Kirk described the results of the prospective survey on hepatitis carried out at Edinburgh and Alton, which show a higher proportion of patients treated with freeze dried products who had consistently abnormal liver enzyme tests, compared with the boys treated with cryoprecipitate. Read more about In a Haemophilia Centre Directors' Hepatitis Working Party meeting, Dr Kirk described the results of the prospective survey on hepatitis carried out at Edinburgh and Alton, which show a higher proportion of patients treated with freeze dried products who had consistently abnormal liver enzyme tests, compared with the boys treated with cryoprecipitate.
Dr Brian Colvin told the Inquiry that around 1982-1983 he was using a significant quantity of commercial concentrate in the hospital due to shortfall in NHS concentrate. Read more about Dr Brian Colvin told the Inquiry that around 1982-1983 he was using a significant quantity of commercial concentrate in the hospital due to shortfall in NHS concentrate.
Dr Brian Colvin told the Inquiry he treated very small children with cryoprecipitate until the mid 1980s. Read more about Dr Brian Colvin told the Inquiry he treated very small children with cryoprecipitate until the mid 1980s.
Dr Brian Colvin confirmed that, by 1975, the haemophilia treating community was aware that there was at least a possibility of chronic liver disease in haemophilia. Read more about Dr Brian Colvin confirmed that, by 1975, the haemophilia treating community was aware that there was at least a possibility of chronic liver disease in haemophilia.
Dr Brian Colvin described in his oral evidence some clinicians' belief that Non-A Non-B Hepatitis was benign as "wishful thinking". Read more about Dr Brian Colvin described in his oral evidence some clinicians' belief that Non-A Non-B Hepatitis was benign as "wishful thinking".