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Dr Peter Jones, director of the Newcastle Haemophilia Centre, along with Sister Maureen Fearns called for a government campaign "to educate the medical profession in the recommended use of blood products".

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Dr Jean Grant noted that the decision not to give blood required a doctor to have "the strength of mind to make the unfashionable decision not to transfuse".

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The 1984 edition of "Notes on Transfusion" noted a preference for haemoglobin to be 10g/dl before major surgery and made express reference to post-transfusion hepatitis and the risks of Hepatitis B and non-A non-B Hepatitis.

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A 2017 study of two large maternity units in Texas and London found that from 1988 to 2000 obstetricians more commonly prescribed two units rather than one unit even when the estimated blood loss and pre-transfusion haemoglobin suggested that one unit would be sufficient.

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The risks of homologous serum jaundice transmissible via blood transfusion were noted in the 1951, 1956 and 1961 editions of Mollison's "Blood Transfusion in Clinical Medicine".

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Dr George Discombe's 1960 textbook highlighted the danger of hepatitis as one that "must never be forgotten when assessing the need for transfusion." He described the common use of blood transfusion for treating pre-operative anaemia as "inexcusable".

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NHS Scotland published clinical standards on blood transfusion.

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The Working Party on Autologous Transfusion produced guidelines for pre-deposit autologous transfusion in 1993.

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The number of referrals to autologous transfusion service doubled in 1997 in Scotland.

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The Chief Medical Officer's National Blood Transfusion Committee published a leaflet titled "Indication Codes for Transfusion - An Audit Tool".

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The April 2004 guideline on caesarean section referred to transfusion only where there is an increased risk of blood loss greater than 1,000ml.

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HTCs were promoted internationally by organisation such as the World Health Organization.

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A study published in 1983 regarding blood use by consultant surgeons, anaesthetists and house surgeons at five hospitals in Wessex found "substantial and unintentional over-ordering" of blood by junior staff.

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A study into blood usage in the Tayside region of Scotland noted that the auditing of blood ordering practices was a much neglected area in surgery.

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The US adopted a similar approach to the UK in terms of carrying out major surgical procedures unless haemoglobin was at least 10.4%.

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Statutory Instruments of the Blood Safety and Quality Regulations 2005 were published.

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Dr Tony Napier's book, "Blood Transfusion Therapy: A Problem-Orientated Approach", was published.

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Mollison's "Blood Transfusion in Clinical Medicine" was published.

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Professor Mollison's book stated that pre-operative transfusions could be avoided if it were a routine practice to determine the patient's haemoglobin concentration at the time when operation is first considered.

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Professor Mollison within his textbook stated that before surgery was undertaken haemoglobin should be raised above 10g/100ml

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