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The 1977 annual return from the Oxford Haemophilia Centre recorded no use of cryoprecipitate at all and greater use of commercial concentrates than NHS.

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In 1979, return records show no cryoprecipitate; a small amount of Elstree Factor 8; 1,078,110 units of Oxford Factor 8; and 906,830 units of commercial (Factorate, Koate, Hemofil).

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The Belfast Haemophilia Centre, based at Royal Victoria Hospital (RVI), was designated as a reference centre.

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Paul Winstanley wrote a note on the imports of blood products into the United Kingdom for medical purposes to Dr Walford and Mrs Walden.

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A paper was presented by Dr Craske at the meeting of the UK Haemophilia Reference Centre Directors, updating the situation regarding AIDS. It was agreed that the patients who had received the same batches of NHS or commercial Factor 8 as the patient who died in Bristol should be followed up.

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A paper on AIDS Investigation was prepared by Dr Craske for the UK Haemophilia Centre Directors.

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Dr Craske presented this 'Appendix B Surveillance of AIDS cases in patients with blood coagulation disorders' paper which had been pre-circulated to directors.

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The President of the British Society for Haematology decided that a Working Party should be formed "to investigate the problem of Aids in relation to the practice of Haematology in the Diagnostic Laboratory."

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Dr Craske explained that there was a "possibility" that transmission by blood and blood products may become "a serious problem" and that in the UK "widespread transmission could occur...unless precautions are taken to exclude donors from the already identified high risk group for AIDS".

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Dr Craske reported to the UKHCDO on the cases of AIDS in different parts of the world given. The number of cases in patients with hereditary disorders of blood coagulation had reached 21 in the USA. 7 cases in Europe had been reported, including two in the UK. Description of a recent study of 7 patients with AIDS associated with blood transfusion.

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Minutes from the meeting of UK Haemophilia Centre Directors where Professor Bloom stated the the UK was recognised throughout the world as having the best organisation for treatment of haemophilic patients and Dr Craske asked for special attention to be given to his report on HTLV III the importance of accurate incidence of HIV in the UK and a need for better reporting

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Appendix collated by Dr Craske containing graphs and histograms based on reports received by Haemophilia Centres on patients who received the same batches of blood products as the Cardiff and Bristol AIDS cases.

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Inquiry publishes expert report on Public Health and Administration

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Dr Lane in a letter to the reference centre directors stated that it was agreed that a meeting should be held "to discuss AIDS in relation to the management of haemophiliacs and the implications for treatment with factor VIII concentrates" and that 10 December was the first date suitable for the majority of participants.

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In a response to Dr Lane, Professor Bloom wrote that "clearly the matter is of great importance and has certainly come to a head with the Australian experience and with the unfortunate death of the Newcastle patient. I am only glad that we had decided in advance of these events to take some action"

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In a letter to Dr Lane, Dr Rizza suggested a number of questions which he thought needed to be considered at the meeting, including whether directors should now switch to using only heat-treated Factor 8 concentrates.

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Dr Lane produced an agenda for the meeting with the Haemophilia Centre Directors.

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In the US over 6,000 cases of AIDS were reported including 52 people with haemophilia and 102 cases in the UK with 3 reported in people with haemophilia.

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Professor Bloom wrote to Dr Ludlam seeking comments on his draft notes of Reference Centre Directors meeting on 14 December 1984.

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Professor Bloom wrote to Dr Lane seeking comments on his draft notes of Reference Centre Directors meeting on 14 December 1984.

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