Transfusion directors in the Joint Steering Committee on Blood Products Production increased the goal of 250,000 donations in March 1973 to 275,000 in June and July 1973. Read more about Transfusion directors in the Joint Steering Committee on Blood Products Production increased the goal of 250,000 donations in March 1973 to 275,000 in June and July 1973.
The main reason for the expansion in producing clotting factor concentrates at the time was to produce more immunoglobulin to prevent rubella in pregnancy, following an outbreak. Read more about The main reason for the expansion in producing clotting factor concentrates at the time was to produce more immunoglobulin to prevent rubella in pregnancy, following an outbreak.
In Lord David Owen's response to parliamentary questions he argued that concentrates were the optimum treatment and commercial product was available. However, UK domestic production should increase and home treatment was desirable. Read more about In Lord David Owen's response to parliamentary questions he argued that concentrates were the optimum treatment and commercial product was available. However, UK domestic production should increase and home treatment was desirable.
Dr Biggs argued that the problem pertained to large available stocks of therapeutic materials in stores because no-one would buy them whilst patients were simultaneously in dire need of this same material. Read more about Dr Biggs argued that the problem pertained to large available stocks of therapeutic materials in stores because no-one would buy them whilst patients were simultaneously in dire need of this same material.
In a meeting it was stressed that Dr Bigg's paper indicated in five years time there may be a need for more material, haemophilia centre directors and transfusion directors approved the contents of the paper and recommended that this document be used as the basis for planning the future requirements for Factor 8 in the United Kingdom. Read more about In a meeting it was stressed that Dr Bigg's paper indicated in five years time there may be a need for more material, haemophilia centre directors and transfusion directors approved the contents of the paper and recommended that this document be used as the basis for planning the future requirements for Factor 8 in the United Kingdom.
Dr John Wallace argued that the threshold required was that an adequate amount of a good quality cryoprecipitate would probably cover most clinical indications for Factor 8 therapy. Read more about Dr John Wallace argued that the threshold required was that an adequate amount of a good quality cryoprecipitate would probably cover most clinical indications for Factor 8 therapy.
The supply of plasma for cryoprecipitate and for sending it to make concentrate at that stage was 300,000 donations a year. Read more about The supply of plasma for cryoprecipitate and for sending it to make concentrate at that stage was 300,000 donations a year.
The initial aim was to supply concentrate made from 250,000 donations for use in home treatment, with the balance being cryoprecipitate. Read more about The initial aim was to supply concentrate made from 250,000 donations for use in home treatment, with the balance being cryoprecipitate.
Sir George Godber wrote to Sir Philip Rogers that the expense of producing commercial or domestic concentrate was thought to be unavoidable in principle and providing domestic supplies would likely be cheaper than purchasing commercial concentrate. Read more about Sir George Godber wrote to Sir Philip Rogers that the expense of producing commercial or domestic concentrate was thought to be unavoidable in principle and providing domestic supplies would likely be cheaper than purchasing commercial concentrate.
Sir George Godber wrote to Sir Philip Rogers that due to increasing expenditure on commercial products being licenced there was a need to consider how far the home supply could be increased, leading to a lower cost. Read more about Sir George Godber wrote to Sir Philip Rogers that due to increasing expenditure on commercial products being licenced there was a need to consider how far the home supply could be increased, leading to a lower cost.