Dr Cumming was the regional transfusion director for Edinburgh and South East Scotland, a professional advocate for plasmapheresis, and was also one of the first three Scottish blood donors to reach 200 donations. Read more about Dr Cumming was the regional transfusion director for Edinburgh and South East Scotland, a professional advocate for plasmapheresis, and was also one of the first three Scottish blood donors to reach 200 donations.
Dr Angela Robinson was an enthusiast for plasmapheresis, and set up a pilot unit in Yorkshire. Read more about Dr Angela Robinson was an enthusiast for plasmapheresis, and set up a pilot unit in Yorkshire.
During this period, government funding was exceptionally constrained, inadequate and difficult to obtain for the redevelopment of BPL and the production of additional plasma for national self-sufficiency. Read more about During this period, government funding was exceptionally constrained, inadequate and difficult to obtain for the redevelopment of BPL and the production of additional plasma for national self-sufficiency.
It was estimated that 74 million international units of Factor 8 could be produced in the UK once the requirements for albumin were met. Read more about It was estimated that 74 million international units of Factor 8 could be produced in the UK once the requirements for albumin were met.
At a meeting of the Blood Products Laboratory, it became clear that PFC's construction would cost more than the sum approved, and that despite a planned 1,500-litre capacity, it would initially only operate at 1,000 litres per week to reduce cost. Read more about At a meeting of the Blood Products Laboratory, it became clear that PFC's construction would cost more than the sum approved, and that despite a planned 1,500-litre capacity, it would initially only operate at 1,000 litres per week to reduce cost.
In Scotland, the national blood service defined self-sufficiency in blood products as the production of enough factor concentrate from a country's own resources to meet clinical need without the need for importation. Read more about In Scotland, the national blood service defined self-sufficiency in blood products as the production of enough factor concentrate from a country's own resources to meet clinical need without the need for importation.
The increasing use of plasmapheresis for collection was pursued as it was a safer base material to manufacture concentrates due to the larger donation that was able to be extracted (the amount of plasma from one donation of whole blood was 40% of that from a donor of plasma by plasmapheresis). Read more about The increasing use of plasmapheresis for collection was pursued as it was a safer base material to manufacture concentrates due to the larger donation that was able to be extracted (the amount of plasma from one donation of whole blood was 40% of that from a donor of plasma by plasmapheresis).
Prescribing choices in England and Wales (being the choices that would be reflected in demand) were being formed when imported commercial Factor 8 filled the gap left by BPL's failure to supply, and this continued into the early 1980's. Read more about Prescribing choices in England and Wales (being the choices that would be reflected in demand) were being formed when imported commercial Factor 8 filled the gap left by BPL's failure to supply, and this continued into the early 1980's.
The quantity of NHS factor concentrate used in Northern Ireland increased dramatically once Northern Irish plasma began being sent to the BPL, as Factor 8 concentrate manufactured at Liberton was sent in return. Read more about The quantity of NHS factor concentrate used in Northern Ireland increased dramatically once Northern Irish plasma began being sent to the BPL, as Factor 8 concentrate manufactured at Liberton was sent in return.
Although Northern Ireland was able to make cryoprecipitate from local blood donors, it was too small to produce factor concentrate itself. Read more about Although Northern Ireland was able to make cryoprecipitate from local blood donors, it was too small to produce factor concentrate itself.