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Dr Kirk provided information in 1976 to the Bournemouth Department of Pathology about a pupil who was negative for HbsAg and HBsAb and had a presumptive diagnosis of non-B hepatitis "probably associated with the transfusion of Kryobulin".

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Dr Painter spoke to some parents in early 1978, and appeared to regard Hepatitis B which had become chronic as potentially leading to a grim future, and a matter of significant concern.

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Dr Craske highlighted to Dr Aromstam that mixing the blood products of different manufacturers might increase the risks of hepatitis and advised that it might be wise to confine students to one type of material.

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Dr Craske asked for people with mild haemophilia to be given NHS Factor 8 for non-urgent operations such as tooth extraction, saying "We have found from observations at Oxford that this is the best way of finding out whether the material is associated with cases of hepatitis".

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Dr Aronstam disagreed with giving mild haemophiliacs NHS Factor 8 for non-urgent operations as he didn't want them to develop hepatitis in any form.

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Dr Craske suggested a trial of NHS concentrate be made to cover non-urgent operations, where other concentrates such as commercial material would be indicated.

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At the 17th meeting of the Haemophilia Reference Centre Directors, at which Dr Aronstam was present, the increased use of cryoprecipitate was discussed in the light of the first known death of a haemophiliac in the UK from AIDS.

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Dr Aronstam switched from using unheated commercial product to using heat treated commercial product (although he continued to use unheat-treated NHS concentrate).

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Dr Aronstam informed Dr Ahmed a patient had lost movement in both of his elbows and shoulders as a direct consequence of him not treating himself properly due to a fear of contracting AIDS, recording that he had advised the patient of "the very small risk numerically" of him acquiring the disease.

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In a letter to Dr Barnes, Dr Aronstam discussed concerns raised by Dr Barnes about Factor VIII affecting "T" cells, noting that the risk was very small and should not deflect from providing appropriate treatment.

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Dr Aronstam wrote to Dr Snape to enquire about a specially accredited pool of Factor 8 donors for new and mild haemophiliacs.

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Dr Snape wrote to Dr Lane discussing a letter from Dr Aronstam regarding the use of hepatitis-reduced Factor 8 where he highlights his immediate concern being securing Factor 8 for two untreated babies, additionally, he was prepared to enter suitable pupils from the College for a prospective hepatitis-reduced product study.

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Dr Aronstam wrote to Professor Bloom confirming that a patient was on the accredited donor pool long before heat treatment became available, it was also confirmed that the patient remained HTLV-3 antibody free.

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Dr Aronstam expressed reservations as to whether it was ethically right in "the current climate" to continue a patients's tolerance inducing protocol.

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Professor Bloom informed Dr Aronstam that a Treloar's pupil had received some of the same batch as the Cardiff patient who had developed AIDS.

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Staff at Treloar's indicated to students sitting together in a large room whether they were HIV positive by going around and saying 'yes' or 'no'.

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Prophylaxis treatment of a patient was discontinued after three years in 1987 because of the risks that immune-suppressive effects would follow.

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Dr Aronstam stated that reports of a hepatitis outbreak at Treloar's had been overstated.

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Dr Aronstam stated, in reference to a Treloar's student, that "he is realistic about AIDS and feels as I do that the benefits of treatment far outweigh the small risk of acquiring this condition".

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A student at Treloar's recalled that pupils were told that they were infected with HIV in the presence of other pupils who had tested negative. He was wrongly informed that he was positive.

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