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Dr Contreras wrote to the DHSS saying that a study of anti-HBc in British blood donors should be undertaken.

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Dr Contreras stated in her oral evidence that the pressure to introduce screening was from the liver disease specialists and the Haemophilia Centre Directors

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Dr Contreras stated in oral evidence she felt it was taking too long to secure funding for a study into surrogate testing

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Dr Contreras stated, upon reflection, she had underplayed the risk of NANBH when writing to Dr Barbara in 1987

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Dr Contreras expressed the view changed for Medicines Control Agency (MCA) from 'maximum benefit at minimal cost' to 'if a measure reduces risk, we should take it' and that she shared this change in view in 1991.

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Mr Justice Burton expressed the view that if a measure would prevent or reduce risk, it should be taken unless the disadvantages outweigh the advantages.

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It was argued during the case that the ALT tests were relatively inexpensive. Mr Underhill QC expressed that cost was not a factor in either ALT testing or anti-HBc testing.

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It was Dr Gunson's belief in the 1980s that the risk of infection was 3% for post-transfusion NANBH

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Mr Justice Burton assessed that the introduction of ALT and anti-HBc testing would have lost 2.5% and 4% of donations respectively but this would have been countered by the moving surplus blood supplies to centres in need. He believed there would not be a major shortage as Dr Gunson had described in 1991.

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Mr Justice Burton concludes that the idea of reducing donor numbers that were unwanted was never discussed by ACTTD or ACVSB and neither ALT or HBc testing overlapped. They should have introduced surrogate testing before 1 March 1988.

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Dr Gunson was a proponent of the minimum risk to maximum safety concept and concurred with both the opinions of Dr Barbara and Dr Contreras

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Dr Dow produced a report that stated the introduction of surrogate screening would have little to no impact on reducing the "already low level of NANBH PTH cases at present reported within the West of Scotland region".

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Dr Forrester reiterated Dr Dow in stating that the cost to benefit ratio of introducing surrogate screening in the West of Scotland means he would recommend against it.

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Dr Cash wrote to Dr Fraser to organise a consensus meeting to discuss NANB surrogate testing methods after Dr Fraser's prospective UK trial was turned down at the NBTS Directors' meeting.

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Dr Cash asked Dr Sandler American Red Cross) to enlighten his team on the current state of surrogate donation testing in the USA

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American Red Cross wrote to Dr Cash in response to his letter to Dr Sandler for an update on surrogate donation testing in the USA. This started after a presentation by Dr Harvey Alter at the 1985 AABB annual meeting. They were also preparing for implementing ALT and anti-HBc testing in blood centers.

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Dr Fraser confirmed to Dr Cash the lack of enthusiasm for a study amongst other regional transfusion directors in England and Wales: only he and Dr Contreras had supported it and the rest of the directors "were not very interested."

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Dr Contreras wrote to Dr Smithies (DHSS) with a proposed study of post transfusion Non-A Non-B hepatitis.

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The Society placed undue reliance on the views of Professor Bloom who was not only chair of UKHCDO but also a principal point of reference when seeking advice.

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By the time of the meeting on 8 October 1983 the realisation had dawned within the Society membership that a crisis was looming.

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