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Dr Craske suggested a trial of NHS concentrate be made to cover non-urgent operations, where other concentrates such as commercial material would be indicated.

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At the 17th meeting of the Haemophilia Reference Centre Directors, at which Dr Aronstam was present, the increased use of cryoprecipitate was discussed in the light of the first known death of a haemophiliac in the UK from AIDS.

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Dr Aronstam switched from using unheated commercial product to using heat treated commercial product (although he continued to use unheat-treated NHS concentrate).

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Dr Aronstam informed Dr Ahmed a patient had lost movement in both of his elbows and shoulders as a direct consequence of him not treating himself properly due to a fear of contracting AIDS, recording that he had advised the patient of "the very small risk numerically" of him acquiring the disease.

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In a letter to Dr Barnes, Dr Aronstam discussed concerns raised by Dr Barnes about Factor VIII affecting "T" cells, noting that the risk was very small and should not deflect from providing appropriate treatment.

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Dr Aronstam wrote to Dr Snape to enquire about a specially accredited pool of Factor 8 donors for new and mild haemophiliacs.

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Dr Snape wrote to Dr Lane discussing a letter from Dr Aronstam regarding the use of hepatitis-reduced Factor 8 where he highlights his immediate concern being securing Factor 8 for two untreated babies, additionally, he was prepared to enter suitable pupils from the College for a prospective hepatitis-reduced product study.

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Dr Aronstam wrote to Professor Bloom confirming that a patient was on the accredited donor pool long before heat treatment became available, it was also confirmed that the patient remained HTLV-3 antibody free.

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Dr Aronstam expressed reservations as to whether it was ethically right in "the current climate" to continue a patients's tolerance inducing protocol.

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Professor Bloom informed Dr Aronstam that a Treloar's pupil had received some of the same batch as the Cardiff patient who had developed AIDS.

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Staff at Treloar's indicated to students sitting together in a large room whether they were HIV positive by going around and saying 'yes' or 'no'.

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Prophylaxis treatment of a patient was discontinued after three years in 1987 because of the risks that immune-suppressive effects would follow.

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Dr Aronstam stated that reports of a hepatitis outbreak at Treloar's had been overstated.

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Dr Aronstam stated, in reference to a Treloar's student, that "he is realistic about AIDS and feels as I do that the benefits of treatment far outweigh the small risk of acquiring this condition".

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Dr Aronstam said to Adrian Goodyear, "we have fucked up, we've messed up, its all gone wrong".

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Adrian Goodyear and four other Treloar's students were told in Dr Aronstam's office that they had HIV.

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Adrian Goodyear had a conversation with Dr Aronstam, who stated "we messed up", "AIDS didn't need to happen" and "the PHLS have let me down".

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Adrian Goodyear recalled that in the early 1980s a small fridge was used for housing NHS material and a larger fridge was used for commercial products.

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A student at Treloar's recalled that pupils were told that they were infected with HIV in the presence of other pupils who had tested negative. He was wrongly informed that he was positive.

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A parent complained about the high dosage of Factor 8 their child was receiving at Treloar's.

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