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William Foege, of the Department of Health and Human Services wrote to Dr Kenneth Woods, of the New York Blood Center, informing of three cases of pneumocystis carinii pneumonia among patients with severe haemophilia A recently reported to the CDC.

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Charles Carman, president of the National Haemophilia Foundation, received correspondence from William Foege, of the Department of Health and Human Services, which informed of three cases of pneumocystis carinii pneumonia among patients with severe haemophilia A recently reported to the CDC.

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Charles Carman, president of the National Haemophilia Foundation, provided patient alerts to be circulated regarding cases of pneumocystis carinii pneumonia among patients with severe haemophilia A, provided ahead of an anticipated CDC report.

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The CDC published its "Epidemiologic Aspects of the Current Outbreak of Kaposi's Sarcoma and Opportunistic Infections" report in the New England Journal of Medicine, examining the recent spike in reported cases of Kaposi's sarcoma.

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Jean Marx published a journal article in the American Association for the Advancement of Science, reporting on the rise in AIDS cases in the US.

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The Lancet published an article on reported cases of altered immunology in haemophilia patients.

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Dr Ian Hann, at this time haematologist at the Royal Free Hospital, attended the Second International Symposium on Infections in the Immunocompromised Host in Stirling, Scotland.

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Professor Ian Hann in his evidence to the Penrose Inquiry shared that the meeting was very gloomy with eminent doctors expressing their dismay at the dramatic new problem and demonstrated the poor state of knowledge and need for research.

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In his evidence to the Penrose Inquiry, Professor Ian Hann said that at the symposium meeting in June 1982 there was also a passing reference to a very small number of haemophilia patients and discussion, which continued for years, as to whether they were immunocompromised because of the large exposure to antigens in their blood products.

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At an open meeting of the PHS Committee on Opportunistic Infections in Patients with Haemophilia held in July 1982, it was recommended that an active surveillance system should be put in place to determine if other suspicious incidences of AIDS were occurring in haemophilia patients.

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In her written evidence to the Inquiry, Dr Walford said that the Med SEB was part of the CMO's chain of command and was staffed by doctors and scientist in an advisory role and that the lead division for the policy areas, covered by Med SEB, was an administrative division, Health Services (HS), which was part of the Permanent Secretary's chain of command.

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Dr Louis Aledort reported to the Congress of the International Societies of Hematology and of Blood Transfusion in Budapest in August 1982 that it was suspected in the US that Factor 8 had resulted in people with haemophilia dying of AIDS, and it was suspected that an infective agent in blood concentrates was the cause.

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The AIDS Literature contributor, Robert Hubbard, extracted articles and investigations in German literature on the risks of contracting HIV through contaminated blood products.

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The CDC published an update on AIDS among patients with haemophilia A, and found 95% of recently reported AIDS infections were either homosexually active men, intravenous drug abusers, Haitians and/or people with haemophilia.

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An article in The Lancet was published on the occurrence of AIDS in an infant who had had a blood transfusion at birth and the possibility of contracting AIDS in such a way.

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Dr Mark Winter (who regularly read the Morbidity and Mortality Weekly Report) told the Inquiry that: "Any clinician looking at this data would have to believe that AIDS was a transmissible disorder and that it could be transmitted by blood and by blood products."

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Ed Cutter wrote a memo to J Ryan, Carolyn Patrick, Wayne Johnson, Ralph Roussell and George Akin advising them to include an AIDS warning in their literature and on its packaging of its Factor 8 and Factor 9 products

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Sir Joseph Smith, former director of the NIBSC and thereafter the PHLS, provided a written statement to the Infected Blood Inquiry.

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Dr Charles Rizza published an epidemiological study of AIDS in patients with coagulation disorders in the UK and its relationship to transfusion with blood products.

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Cornelis Smith, coordinator of the Netherlands Haemophilia Society, provided a written statement to the Infected Blood Inquiry.

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