Subscribe to Search results

Sales figures for the year ending October 1976 showed that Hemofil and Kryobulin were the most used products, followed by Factorate and Profilate.

Published on:

Survey of commercially-produced and NHS-produced Factor 8 concentrates refers to Hemofil, Kryobulin and Profilate as three main products licensed in the UK.

Published on:

Profilate HT gained market share as a consequence of growing confidence that its technique of "wet heat treatment" reduced, although did not eliminate, the risk of infection with non-A non-B Hepatitis as well as inactivating HIV.

Published on:

Profilate licensed with the following warning: "This product is prepared from units of human plasma which have been tested and found nonreactive for Hepatitis Associated Antigen. However, it is recognized that presently available methods are not sensitive enough to detect all units of potential infectious plasma and the risk of transmitting hepatitis is still present".

Published on:

Over the years the text of the Profilate warning was amended to take account of changes to screening tests, but the final sentence remained unchanged.

Published on:

Profilate HT was provided on a named patient basis in the UK

Published on:

The licensing authority required references to heat treatment to be that it was intended to "reduce the risk of transmission of infectious agents" rather than making claims about it reducing the risks of HIV or non-A non-B Hepatitis by name.

Published on:

In terms of the distribution of market share for commercial Factor 8 products, Factorate accounted for 42%, Koate for 18% and Profilate and Kryobulin both accounted for around 11% of total usage.

Published on:

Armour,/Alpha, Travenol/Hyland, Miles/Cutter and Immuno all confirmed that their plasma came from plants that were licensed by the FDA and that the origins of their plasma were identifiable

Published on:

Professor Bloom stated that Profilate HT had the largest share of the commercial market.

Published on:

Hyland Therapeutics closed a plasma centre in Puerto Rico.

Published on:

Hyland Therapeutics closed the Mexico City plant (which used Mexican sourced plasma).

Published on:

Hyland Therapeutics closed that their sole plant in Lesotho.

Published on:

When AIDS cases first came to public attention in 1981 immigrants from Haiti were found to be at high risk of infection and hence unsuitable as donors.

Published on:

Dr Kingdon occupied various positions in Hyland Therapeutics.

Published on:

The figure of 1,000 donors appeared on a product label for Kryobulin Red (made with European plasma).

Published on:

Companies could voluntarily submit product data sheets to a compendium produced annually by the Association of British Pharmaceutical Industry ("ABPI").

Published on:

Data sheets and product leaflets relating to Kryobulin did not mention AIDS, HTLV-3, LAV or HIV.

Published on:

According to Dr Kingdon, the United States Federal Drug Administration (FDA) mandated source plasma as a licensed product. In order to obtain a licence for the production of source plasma every collection centre must be inspected annually by the FDA.

Published on:

According to Dr Kingdon, all plasma used for the production of concentrates in the United States had been obtained from donors in the United States.

Published on: