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The Chief Medical Officer issued a statement which reported that three patients who had suffered from vCJD had been blood donors, and a fourth was suspected of having been one too.

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The Lothian Ethics Committee initially took the view that no attempt should be made to trace nor inform recipients of implicated donations, and after being asked to review its position in October 1997, reiterated its earlier advice.

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Dr Patricia Hewitt spoke informally to Professor Ian Kennedy regarding a study to check on recipients of those blood donors who later developed vCJD.

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The Coroner wrote to the Secretary of State for Health to express his concern that Mark Buckland had not been told of his being infected with vCJD earlier.

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Professor Collinge's team reported the development of a prototype blood test to diagnose vCJD in symptomatic individuals which could be further developed into a large-scale screening test for asymptomatic vCJD prion infections.

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Dr Will and others published an article in "The Lancet" regarding their findings pertaining to a new variant of CJD in the UK.

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The Department of Health made recombinant available to all children under 16 and new patients in England, matching what was already provided in Scotland, Wales and Northern Ireland.

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The MSBT agreed that any donor who had received a blood transfusion after 1 January 1980 should be excluded from donating.

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A summary of the inquest into the death of Mark Buckland was released.

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Caroline Flint responded on behalf of the Secretary of State for Health to the Coroner's letter regarding Mark Buckland not having been told of his situation earlier.

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Dr Patricia Hewitt, in her written statement to the Inquiry, explained that the initial decision not to inform recipients who had received vCJD was made by the Department of Health.

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From 1 April 1998 donors who had had brain surgery before August 1992 were permanently deferred.

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Blood transfusion services throughout the UK were required to ask all blood donors whether they had a family history of CJD and where a close family member with CJD was a direct bloodline relative the potential donor was to be advised not to give blood.

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Inquiry confirms second round of appointments of expert group members

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The Standing Advisory Committee on Transfusion Transmitted Infections proposed a study to check on recipients of those blood donors who later developed vCJD.

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The Lothian Research Ethics Committee refused the National Creutzfeldt-Jakob Disease Research and Surveillance Unit's application for renewed ethical approval of the Transfusion Medicine Epidemiology Review study.

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Professor Doyal wrote to Dr Hewitt of the National Blood Authority expressing his view that donors who were told their blood would not be used must be informed why that was, and that it would be illegal and immoral to allow someone to give blood when it was known that the donation would be destroyed.

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A letter sent by the Scottish Office to NHS Trust medical directors stated that they had been told by ethics experts and advisory bodies that there was no need to inform patients who had received nvCJD-implicated blood components or products.

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"The Lancet" published an article which included reference to a case where a patient who had received a donation of blood in 1996 from an infected donor subsequently died of vCJD.

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An NHS Blood and Transplant meeting discussed and agreed on various measures on the management of patients who received blood from donors who later developed vCJD.

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