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The most recent annual report for Systematic Reviews Initiative activities, covering the period of October 2022 to October 2023, demonstrates that it has contributed to 20 international and national guidelines.

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NICE issued a Quality Standard which reads: "People who may need or who have had a transfusion are given verbal and written information about blood transfusion."

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In 2001 the CMO's National Blood Transfusion Committee was established in England.

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Dr Archibald Prentice said in his written statement "I knew the risk of Hepatitis B as I was exposed to it as a Senior Registrar. A contaminated bag of platelets from a Hep B positive donor had burst ... in the late 1970s ... One of my colleagues had been sprayed by plasma from a Hepatitis B positive patient and became very sick with Hepatitis B."

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Dr Prentice, who was a consultant haematologist in Plymouth from 1981 described efforts to reduce the use of blood by surgeons wherever possible and to persuade colleagues to use saline instead of blood products for hypo-volaemic or shocked patients.

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Dr Archibald Prentice's concern about over use of blood led to a reduction in usage of blood and blood products in operations by around 25%.

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The UK became one of the first countries to establish truly national haemovigilance through SHOT.

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Darren Rawson received a letter from the chief executive of Hull and East Yorkshire Hospitals NHS Trust which said: "In England and Wales blood began to be heat treated to destroy any viruses during 1985 and slightly later than this in Scotland. According to our records you were given blood in 1988 and this was done in the belief that the blood from the transfusion service was safe and heat treated.

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Letter from Dr Robinson to Dr Metters provided an outline of the structure of the Standing Advisory Committee on Transfusion Transmitted Infections

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Sir Kenneth Calman wrote that problems relating to blood, in particular those relating to vCJD, indicated the need to look more closely at clinical and research progress in blood transfusion practice, and at measures to reduce or avoid problems associated with blood transfusion.

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Tom Sackville's responsibilities as the Parliamentary Under-Secretary of State for Health included blood. Key decisions were taken by his predecessors, ministerial superiors or other senior government officials.

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A note recording that Tom Sackville did not approve the principle of ex-gratia payments at a meeting with Dr Andrzej Rejman, John Canavan and Dr Jeremy Metters.

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The Government had never accepted the case for no fault compensation for medical accidents.

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While there was sympathy for Hepatitis C suffers, Tom Sackville and his colleagues were aware of the arguments against compensation.

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The Government was concerned by the potential costs of a Hepatitis C payment scheme.

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Tom Sackville noted that the distinction between the position in respect of HIV and Hepatitis C was a tricky one and asked for advice and a line to take.

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A memo was provided to Tom Sackville outlining the Government's policy and arguments on no fault compensation at the time.

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A paper was prepared, which set out the Government's resistance to no fault compensation.

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Tom Sackville wrote to David Porter confirming the Government had no plan to extend the HIV payment scheme to those infected with Hepatitis C.

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A memo from Dr Andrzej Rejman and John Canavan to Tom Sackville and to Dr Jeremy Metters outlined the arguments for and against ex-gratia payment. It noted that it was open to ministers to make ex-gratia payment and sought ministers' views on whether it should be further considered.

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