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Professor John Cash asked Dr Ginger Rosenberg at Chiron for access in due course to antibody testing kits for evaluation purposes.

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Robert Panton requested funding for the pilot study.

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Ortho organised a meeting in London with representatives from both the English and Scottish blood services to look at the preliminary UKBTS data.

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It was "important that the UK Blood Transfusion Services should act in unison on this subject" of HCV testing.

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Dr Lloyd reiterated his concern that the UK was "dragging its feet over testing" and was running the risk of "accepting the lowest common denominator" approach.

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Dr Boulton insisted that the screening of donors for HCV antibodies should be introduced at the earliest possible opportunity.

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At a meeting of the SNBTS directors Dr Gunson reported the agreement to conduct a UK study, with 1,000 samples to be sent from the UK to Chiron for blind testing.

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On 7 January 1991, at a meeting of the NBTS/SNBTS Liaison Committee it was reported that no decision had been taken by the Department of Health on the implementation or funding of anti-HCV testing.

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Professor Cash insisted that HCV testing be discussed.

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Scotland were under pressure from the SNBTS to fund the introduction of additional virological testing for HCV, but wanted to know what the UK planned to do first.

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An HCV test would be available towards the end of 1989, but there was a great deal of work to do regarding manufacturing and trials to get to that point.

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The anticipated commencement date for the Ortho and Abbott 1&2 tests was 1 July 1991.

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Professor Cash asked for "some idea of the current time schedule to the point of full marketing in the UK for full donation testing."

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Dr Gunson and Dr Perry had argued that there was already sufficient data for ACVSB to recommend to ministers the introduction of a first-generation Hepatitis C donation screening as soon as possible, but their views were rejected.

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Professor Cash suggested that the evaluation of second-generation tests might be modified to accommodate the screening programme in Newcastle.

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Professor Cash noted that Dr Gunson conveyed his concern that the Department of Health had still not decided on a start date, and it now seemed the earliest possible date would be May or June 1991.

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Dr Mortimer reported on developments in the pilot study, now comparing two further candidate screening tests, from Wellcome and UBI, with results from the Ortho and Abbott test kits.

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In a minute to Scotland's Deputy Chief Medical Officer Dr Young, Dr McIntyre stated: "Things are moving very fast on the Hepatitis C front" and he anticipated that at the next Advisory Committee on the Virological Safety of Blood meeting it would be decided that "there is no alternative but to recommend the introduction of the test."

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It was reported in "Blood Bank Week" that Chiron Corporation hoped to have their test to screen blood for non-A non-B Hepatitis available for clinical trials by the end of the year.

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Dr Gunson produced a paper reporting on the use of the RIBA II confirmatory assay to assess reactive results from the first-generation Ortho and Abbott study.

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