Subscribe to Search results

Responding to the requirement to seek Home Affairs Committee clearance before policy approval, Andrew Lansley stated in his written statement that "The Deputy PM will have responded giving HA Committee clearance."

Published on:

Recommendations of financial relief in relation to the contaminated blood review were presented to Anne Milton which set out a variety of options for the Government to consider.

Published on:

A report was produced entitled "Review of the support available to individuals infected with Hepatitis C and/or HIV by NHS-supplied blood transfusions or blood products and their dependants."

Published on:

Anne Milton set out, in a undated letter to David Cameron, a summary of the report by the Department of Health on the financial support available for individuals infected with Hepatitis C/HIV.

Published on:

In Roderick Murray's "Viral Hepatitis Bulletin of the New York Academy of Medicine", he showed that an exceptionally small amount of blood containing a virus could be infective.

Published on:

In Barker et al's "Transmission of Serum Hepatitis", featured in the Journal of the American Medical Association, the high infectivity of hepatitis was echoed.

Published on:

In Dr Rosemary Bigg's book "The Treatment of Haemophilia A and B and von Willebrand's Disease", she cited Roderick Murray's 1955 work, which identified that even an exceptionally small amount of blood containing a virus could be infective.

Published on:

A study carried out by Gocke said that, in total, 74% of the recipients of blood con_taining the Australia antigen exhibited either hepatitis or an immune response.

Published on:

At a meeting of blood transfusion officers they discussed the proposal that the pool size used at the Cambridge drying plant for plasma should be reduced to a size of no more than 10 donors.

Published on:

The British Medical Journal article had a footnote which said that "We understand that only small pools are now used by the Ministry of Health for the preparation of blood products."

Published on:

A study of British Army records concluded that plasma was more icterogenic than whole blood and one reason for this was likely because one bottle of plasma came from a pool to which many donors contributed.

Published on:

In a letter to Dr Maycock, Dr Drummond stated that he did not think it was justifiable to continue to issue large pool plasma which had a 10% incidence of homologous serum jaundice as opposed to 1% for small pools, and that were a case of this to go to court it would not be justifiable since it was practicable to make small pools.

Published on:

A study by Biggs in the British Journal of Haematology described the process of preparing Factor 9 concentrate using 45-50 litres of plasma.

Published on:

Pools used to prepare antihemophilic factor were 14-22 litres in size. This amounted to the use of pools made from a maximum of 90-110 donations. There was said to be no "contra-indications to the prolonged or repeated use of the product."

Published on:

Dr Peter Wolf commented "The risk of contamination of blood with the virus of infective hepatitis limits a single fractionation batch to a donor pool of 50" but "Human A.H.F. concentrate, produced in this way at multiple centres throughout the country, could provide sufficient to treat all the known classical haemophiliacs in Great Britain."

Published on:

Dr Maycock and Leon Vallet proposed to "retain the present pool size (30L) because of the risk of transmitting serum hepatitis."

Published on:

A working party on human antihaemophilic globulin decided "it was considered inadvisable, when planning increased production, to increase the plasma pool volume much above this size (30-40 litres in volume), unless further observations indicated that the risk was smaller than the present series of cases suggested."

Published on:

Dr Maycock wrote that in the UK antihaemophilic globulin ("AHG") was made from donor pools of 60-100 donors, and described a "paucity of reports of hepatitis" associated with this.

Published on:

Dr Jean Grant recorded that "It has been found that a minute fraction of a millilitre of virus-laden blood was enough to cause hepatitis and it was for this reason that the production of large-pool plasma, made from the contributions of more than 300 donors, was abandoned in favour of limited pools derived from not more than ten donors."

Published on:

Dr Robert Cumming and colleagues commented "Because of the risk of transmitting serum hepatitis, small-pool operation is preferable, in preparing antihaemophilic fractions."

Published on: