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The outcome of the Hepatitis C lookback in England was formally reported. 50% of tested recipients were found to be infected with Hepatitis C. 4,432 recipients of 6,687 blood components were identified.

Published on: 05 August, 2024

The Scottish Office wrote to SNBTS asking them to take forward "as expeditiously as possible" a Hepatitis C lookback for all of Scotland and to keep the SHHD informed.

Published on: 05 August, 2024

The Standing Advisory Committee on Transfusion Transmitted Infections noted that "the issue needs resolution and will be examined in more detail by a group to be convened to consider it further."

Published on: 05 August, 2024

Dr Gunson and Dr Cash "agreed [that]...it would not, after we start anti-HCV donation screening, be appropriate to introduce a systematic look-back programme on previous recipient - as was done for HIV-1."

Published on: 05 August, 2024

Professor Cash, on behalf of SACTTI, produced a paper for the MSBT on the merits of adopting a Hepatitis C lookback policy. It stated that a Hepatitis C lookback could be based on the current procedures of HIV lookback.

Published on: 05 August, 2024

Dr Gunson of the National Blood Transfusion Service wrote to Professor Cash of the Scottish NBTS, advising him of discussions had at ACVSB and plans to table the subject in upcoming meetings, and the intention to ask John Craske for a copy of the questionnaire for counselling as compiled by Dr Julia Heptonstall.

Published on: 05 August, 2024

In a letter to Dr A Keel, Professor Franklin provided an update on the HCV lookback exercise, particularly the lack of funding needed to trace some patients, and considered the issue of RIBA indeterminates.

Published on: 05 August, 2024

In a letter to all doctors, Scottish Health Department CMO, Dr R E Kendell, provided guidance relating to the recently announced HCV lookback exercise and sought their assistance in identifying patients infected with HCV through blood transfusion.

Published on: 05 August, 2024

At a meeting of the SNBTS Medical & Scientific Committee It was recorded that "in the light of national events, it was agreed no 'Look Back' should be introduced at present."

Published on: 05 August, 2024

At a meeting of the Advisory Committee on the Microbiological Safety of Blood and Tissues for Transplantation Dr Robinson presented a report on the HCV lookback.

Published on: 05 August, 2024

At a meeting of the Advisory Committee on the Microbiological Safety of Blood and Tissues for Transplantation Dr Robinson presented the SACTTI's paper on Hepatitis C Lookback. Professor Arie Zuckerman raised concerns that interferon was not licensed for treatment of Hepatitis C-related disease and ribavirin was noted to be "even more costly."

Published on: 05 August, 2024

At a meeting, Dr Gillon briefed the SNBTS Medical and Scientific Committee on the Hepatitis C lookback.

Published on: 05 August, 2024

In a letter to Dr Gunson, Professor Cash proposed delaying any lookback programme until further UK deliberations had taken place.

Published on: 05 August, 2024

In a letter to Professor Cash, Dr Gunson noted the RTCs did not have access to anti-HCV testing material, and recommended usual investigations in reported cases involving a transfusion-associated NANBH.

Published on: 05 August, 2024

Dr Keel wrote to Professor Franklin to discuss the HCV lookback exercise in 1998, and noted it could not be considered formally closed until reasons for non-traceability of components or recipients were logged on the lookback register.

Published on: 05 August, 2024

Professor Cash wrote to Dr Jack Gillon to discuss the Medical & Scientific Committee agreement to use donor counselling guidelines in leaflet form within RTCs.

Published on: 05 August, 2024

A letter from Professor Bloom and Dr Rizza to Haemophilia centre directors stated that many directors reserved supplies of cryoprecipitate for the treatment of children.

Published on: 08 August, 2024

In an article Dr Biggs said: "Cryoprecipitate is a simple concentrate made from plasma at all Regional Transfusion Centres. Cryoprecipitate is much superior to plasma for the treatment of haemophilia A patients but the material is very variable from one sample to another and the potency cannot be known before it is used."

Published on: 08 August, 2024

Porcine plasma was first used to treat a patient in 1954.

Published on: 08 August, 2024

Early in the Second World War, Dr Edwin Cohn had developed ways of separating plasma into separate protein fractions, by treating whole blood with anticoagulant, separating off the plasma, and "fractionating" the plasma under varying conditions of acidity and proportions of ethanol so as to separate one fraction of it from another.

Published on: 08 August, 2024

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