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Dr Lane was authorised to proceed with the stop-gap project. The DHSS anticipated that the sum of £750,000 would be available for the capital development of BPL in 1980/1981.

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It was not until this time that Dr Lane was given formal authority to proceed to tender with MARP01, the name given to the stop-gap proposal.

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Dr Gunson tabled a paper concluding that the number of plasmapheresis facilities should be increased. The Advisory Committee of the NBTS agreed to set up a Working Party and liaise with Scotland.

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The Working Party to Advise on Plasma Supplies for Self-Sufficiency in Blood Products published a preliminary report estimating costs of plasmapheresis compared favourably with the estimated cost of obtaining the same weight of whole blood.

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A Policy Steering Group for the Redevelopment of BPL meeting was held.

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Angus MacPherson wrote a letter to John Harley discussing the results of the shift working trial and outlining that the necessary building works could be completed in approximately two and a half years.

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Planning was eventually under way for a new building to constitute BPL at Elstree.

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A meeting of regional transfusion directors was held at BPL to receive information concerning the future requirements for increased supply of plasma for fractionation.

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A report was published titled "Value of SAG-M Systems in the Provision of Plasma Products".

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BPL noted that for the first year since Hepatitis B testing had first been carried out none of the five-litre plasma pools screened for Hepatitis B at regional transfusion centres and dispatched to the BPL had tested positive for Hepatitis B.

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Plasmapheresis grew as a source of plasma and, by 1986/1987, had given rise to just over 10% of the plasma sent to BPL.

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A new scheme of distribution for NHS Factor 8 concentrates was introduced. The amount to be sent to each region would be calculated by reference to the number of patients who had been reported as being treated in the haemophilia centres of that region in 1974.

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SAG-M was most likely introduced in September 1982.

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In Parliament, Dr Owen described the Government's policy as making the NHS self-sufficient in the production of Factor 8 as soon as "practicable".

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Elstree and Oxford were producing around 15 million international units of Factor 8 and NBTS was producing about the same amount in terms of cryoprecipitate.

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The additional donations required to meet self-sufficiency targets were calculated after detailed discussions between DHSS and regional transfusion centres. Some regions produced no fresh frozen plasma for factor concentrate at all, whereas Oxford and the North East Thames were producing large quantities.

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The Medicines Inspectorate began its inspection of BPL and concluded that planning for essential improvements should begin immediately and called for urgent action. It observed the current position was not a recent situation.

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Following the redevelopment of BPL, an increase in plasma supplies and factor concentrate production occurred.

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The Northern Regional Health Authority was offered increased capital and the West Midlands Regional Health Authority was offered an increased revenue allocation in order to produce the plasma required.

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In considering what needs the Department of Health should plan for, a review of blood and blood products in 1976 noted that there was little information to show whether current practices represented optimal use of products or whether figures were misleading due to wasteful practices.

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