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The Council of Europe issued its recommendations which included avoiding, the use of coagulation factor concentrates prepared from large plasma pools and informing people with haemophilia of the potential health hazards of haemotherapy and the possibilities of minimising these risks.

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At the Hepatitis Working Party's meeting the position in relation to the occurence of cases of AIDS in haemophilia A patients treated with commercial factor concentrates was reviewed. It was stated that there had been two cases of the syndrome in the UK.

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Dr Delamore stated that he appreciated that the freeze-dried preparations were much more suitable for home treatment, which he now hoped to institute in selected cases.

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Except for two patients on a period of prophylaxis with commercial concentrate noted below, all 10 other severe haemophiliac participants were treated with NHS freeze-dried factor-VIII concentrate prepared by the Lister Institute Laboratories.

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Inquiry publishes financial annual report

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The 1977 annual return from the Oxford Haemophilia Centre recorded no use of cryoprecipitate at all and greater use of commercial concentrates than NHS.

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In 1979, return records show no cryoprecipitate; a small amount of Elstree Factor 8; 1,078,110 units of Oxford Factor 8; and 906,830 units of commercial (Factorate, Koate, Hemofil).

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The Belfast Haemophilia Centre, based at Royal Victoria Hospital (RVI), was designated as a reference centre.

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Paul Winstanley wrote a note on the imports of blood products into the United Kingdom for medical purposes to Dr Walford and Mrs Walden.

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A paper was presented by Dr Craske at the meeting of the UK Haemophilia Reference Centre Directors, updating the situation regarding AIDS. It was agreed that the patients who had received the same batches of NHS or commercial Factor 8 as the patient who died in Bristol should be followed up.

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A paper on AIDS Investigation was prepared by Dr Craske for the UK Haemophilia Centre Directors.

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Dr Craske presented this 'Appendix B Surveillance of AIDS cases in patients with blood coagulation disorders' paper which had been pre-circulated to directors.

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The President of the British Society for Haematology decided that a Working Party should be formed "to investigate the problem of Aids in relation to the practice of Haematology in the Diagnostic Laboratory."

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Dr Colvin mentioned that there were tiny amounts of an NHS small pool heat-treated concentrate available around the middle of 1984.

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At the NETR Haemophilia Working Party, it was suggested that until a positive test for AIDS and/or a vaccine is developed the use of blood products should be avoided. However this did not lead to any change of policy at The Royal London.

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Dr Colvin clarified that the statement he made that "there is no reason to spurn commercial concentrate" implied that he did not recommend that they don't buy commercial concentrate at all.

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Dr Colvin stated in his oral evidence "if you had abandoned all surgery except for the most life-saving and the home treatment programme and if you had cut back on dosage...the consequences of the temporary withdrawal of all blood products in the way that Dr Galbraith perfectly understandably recommended was a probable."

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Dr Colvin reported that there were 41 patients infected with HIV, of which 31 had severe Haemophilia A, 9 had moderate/mild Haemophilia A and 1 had Haemophilia B. He recalled three children who were infected with HIV from their treatment and one partner of a patient who was infected.

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Dr Craske explained that there was a "possibility" that transmission by blood and blood products may become "a serious problem" and that in the UK "widespread transmission could occur...unless precautions are taken to exclude donors from the already identified high risk group for AIDS".

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Dr Craske reported to the UKHCDO on the cases of AIDS in different parts of the world given. The number of cases in patients with hereditary disorders of blood coagulation had reached 21 in the USA. 7 cases in Europe had been reported, including two in the UK. Description of a recent study of 7 patients with AIDS associated with blood transfusion.

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