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Cardiff's Annual Return for 1984 recorded an increase in the use of cryoprecipitate, a greater increase in the amount of NHS concentrates used (1,704,313 units), and a reduction in the amount of commercial concentrates (861,677 units). The individual patient data filed with the 1984 return showed the treatment of a child born in 1971 with cryoprecipitate. The individual patient data filed with the 1984 return showed the treatment of a child born in 1983 with cryoprecipitate.

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Dr Rizza was in support of plans to set up an AIDS screening programme. The terms in which he wrote are instructive: "it is important that we act quickly to set up screening tests to detect the patients who might be at risk of developing the full blown condition."

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There was almost no cryoprecipitate used for the treatment of Haemophilia A. 1,636,580 units of NHS Factor 8 were used; over 4.5 million units of commercial concentrates were used.

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In 1984 there were almost no cryoprecipitate; 1,919,162 units of NHS Factor 8; and 3,907,595 units of commercial concentrates.

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The individual patient data shows people being treated with NHS and commercial concentrate and with more than one type of commercial concentrate.

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In December 1984, Oxford Haemophilia Centre placed its first order for heat-treated concentrates

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In Bradford, in 1982, there was a move away from the use of cryoprecipitate to factor concentrates and the introduction of home treatment

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In Bradford, in 1983, no cryoprecipitate was used for the treatment of patients with Haemophilia A; all treatment was with concentrates (NHS, Factorate and Kryobulin)

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In a Blood Transfusion Services meeting on 4th December 1984 it was said, theoretically, "heat-treated material was likely to be safer than non-treated material"

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Local directors in Bradford, having discussed the Elstree protocols, did not want interim heat-treated product that would only likely be available two or three months and preferred to wait until April when "a better product is promised"

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In 1976, St George's Hospital had begun to shift away from cryoprecipitate and towards concentrate, predominantly commercial. Predominantly still cryoprecipitate used.

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In 1983, an annual return for St George's Hospital showed a significant shift to commercial concentrate (Armour) for both hospital and home treatment, with very little cryoprecipitate and some NHS concentrate

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The annual return for Guy's for 1982 shows that 229,675 units of concentrate were used in the treatment of 21 patients with Haemophilia A

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The annual return reported 160,575 units of concentrate were used in the treatment of 17 patients with Haemophilia .

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Cryoprecipitate was used for the treatment of Haemophilia A to an extent, but most treatment was with NHS concentrate.

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When Dr Winter sent sera to Dr Tedder for testing in October 1984, all but one was positive for HIV. About half of those were children and some were people with moderate haemophilia.

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Dr Winter recalled Professor Bloom saying "You are mad to switch. There will never be HIV in BPL Factor VIII."

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Dr Mark Winter described it as "utterly bizarre" for doctors to discuss not providing results unless the patient asks for it.

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Dr Colvin did use substantial quantities of NHS Factor 8 (1,100,392 units) as well as 148,540 units of cryoprecipitate and 388,654 units of commercial concentrate (Koate,
Factorate, Hemofil and Kryobulin) for the treatment of 78 patients with Haemophilia A.

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It appeared that substantial quantities of NHS Factor 8, cryoprecipitate and commercial concentrate were used for the treatment of patients.

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