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A study by J Spero reported persistent abnormalities in liver-function for haemophiliac patients. A significant number demonstrated results of anti-HBc (56 of 65, or 86 percent). Many showed signs of chronic liver disease.

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Dr Mayne cited a paper by J Spero that structural abnormalities of the liver were described in patients. The paper discusses a study on haemophiliacs deficient in factor VIII or IX where significant numbers showed signs of chronic liver disease.

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A report by Dr Preston that revealed 77 percent of haemophiliac patients following a systematic screening in Sheffield were revealed to have abnormal liver-function.

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Dr Preston told the Lindsay Tribunal in 1978 that there was a broad spectrum of chronic liver disease which was both concerning and surprising.

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After reading the 1978 Sheffield/Preston paper, Dr Colvin accepted that clinicians could no longer work on the assumption that the absence of overt or acute signs was a reliable indicator that a person would not develop NANBH.

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Oral evidence describes how during the 1970s, Dr Davies had a preference for locally sourced materials due to the risks associated with hepatitis and that novel viruses may be introduced to the local population.

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Some evidence has held that doctors during the 1970s, 1980s and 1990s were part of a medical regime centred around a more paternalistic paradigm. However, alternate evidence offered to the inquiry have held that regardless of the time period, there are certain fundamental ethical norms and principles which lie at the heart of the medical profession including autonomy, beneficence and non-maleficence.

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Evidence presented to the inquiry held that while most doctors took the view that not discussing the risks associated with blood products with patients would not result in deterring patients from using the various treatments anyway. However, Professors Farsides and Kerridge on the medical experts panel to the inquiry disagreed, stating until one has disclosed all the risks to a patient, then one cannot assume patients are making a fully informed decision.

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Speakers from the Medical Ethics Experts Panel held that it was ethically wrong not to explain the risks of treatment to patients.

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Speakers from the Medical Ethics Experts Panel held that it was ethically wrong not to promptly provide patients with the outcomes of their diagnosis and test results.

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In Edinburgh the principal product used in 1976 was cryoprecipitate.

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In Edinburgh the principal product used in 1977 was cryoprecipitate.

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In Edinburgh the principal product used in 1978 was cryoprecipitate.

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In Edinburgh the principal product used in 1979 was cryoprecipitate.

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From 1980, when Professor Ludlam arrived in Edinburgh, the volume of NHS concentrates used exceeded the volume of cryoprecipitate for the first time.

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In 1974 - 1975, at the Glasgow Royal Infirmary while commercial concentrates were in use cryoprecipitate was the predominant product.

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During the 1980, the haemophilia centre at the Royal Hospital for Sick Children ("RHSC") in Yorkhill, Glasgow, provided haemophilia treatment to children from the Glasgow area and across the West of Scotland. 55 had Haemophilia A, 14 had Haemophilia B and 1 had von Willebrand disease.

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The annual return taken from Glasgow in 1976, held that the use of concentrates (more NHS than commercial, although Profilate, Factorate, Koate and Hemofil were all used) exceeded the use of cryoprecipitate.

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The annual return taken from Glasgow in 1977, held that the use of concentrates (more NHS than commercial, although Profilate, Factorate, Koate and Hemofil were all used) exceeded the use of cryoprecipitate.

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The annual return taken from Glasgow in 1978, held that the use of concentrates (more NHS than commercial, although Profilate, Factorate, Koate and Hemofil were all used) exceeded the use of cryoprecipitate.

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