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Dr Ball's recalled that, as a proportion of children registered per centre in the UK, Alder Hay "was one of the highest (if not the highest) proportion of HIV positive haemophiliacs."

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Data from UKHCDO suggested that 13 children were infected with HIV, a July 1987 report recorded 16 cases, and Dr Ball recollected approximately 12 boys who were HIV positive.

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By 1989, a large proportion of the clinical notes of children affected by HIV were missing essential treatment and decision-making details.

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There was no system of batch dedication to reduce donor exposure in Liverpool.

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Evidence confirmed that DDAVP was not in use until after 1988/89 in Liverpool. Dr Martin argued it was "of limited value, and difficult to use with small children."

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A report in July 1987 recorded 16 cases of children being infected at Alder Hey with HIV, though UKHCDO figures suggested 13 and Dr Ball recollected approximately 12.

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Annual Returns for Alder Hey Children's Hospital 1978 recorded the use of cryoprecipitate and both NHS and commercial concentrate.

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Annual Returns for Alder Hey Children's Hospital 1979 recorded the use of cryoprecipitate and both NHS and commercial concentrate.

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Annual Returns for Alder Hey Children's Hospital 1980 recorded the use of commercial concentrate (Factorate) increased.

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Annual Returns for Alder Hey Children's Hospital 1981 recorded Alder Hey treated its haemophilia patients almost exclusively with concentrate (both NHS and Factorate).

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Annual Returns for Alder Hey Children's Hospital 1982 recorded Alder Hey used almost exclusively concentrate, most of which was commercial.

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Annual Returns for Alder Hey Children's Hospital for 1983 recorded the almost exclusive use of concentrate, which was mostly Factorate.

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In 1984 Alder Hey treated its Haemophilia A patients only with concentrates, both commercial and NHS.

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In 1986 Alder Hey treated its Haemophilia A patients only with factor concentrate.

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Dr Savidge's report in 1992 revealed that Stephen, at the age of two years old, was treated with US commercial concentrates on 32 occasions in the course of 1982. He was treated with US commercial concentrates repeatedly again in 1983 and 1984, including as late as December 1984.

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Dr Savidge continues in his report stating Stephen twice received unheated US concentrates in early 1985.

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Dr Savidge assessed the treatment of infants and children throughout the late 1970s and early 1980s stating "The lack of consideration and disregard of the then current therapeutic recommendations for the treatment of children under the age of 4 years regarding the use of cryoprecipitate in this case was negligent...The overwhelming use of commercial U.S. concentrates in preference to cryoprecipitate or NHS factor VIII is remarkable,"

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Dr Savidge considered Dr Martin's treatment for Stephen "at these times when heat treated concentrates were commercially available was negligent."

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Information from legal claims relating to other children treated at Alder Hey revealed the same approach to treatment. For one patient a note detailed that NHS concentrate should have been preferred to commercial from about mid-1983 but supplies were inadequate to adhere entirely to this counsel of perfection.

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A DHSS analysis of legal claims acknowledged it would be indefensible if any commercial concentrate given in 1985 was not heat-treated.

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