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The 1977 Annual Returns for Alder Hey Children's Hospital recorded 643 packs of cryoprecipitate; in relation to concentrates, no figures were provided.

Published on: 30 September, 2024

The care of boys with haemophilia was shared between Dr Frank Boulton and Dr John Martin. They shared a regular integrated clinic at the Liverpool Royal Infirmary/Royal Liverpool Hospital. The haemostasis diagnostic laboratory at the LRI was Dr Frank Boulton's responsibility.

Published on: 30 September, 2024

Dr Martin, a consultant paediatrician, in a letter to BPL noted that they normally received their factor VIII via the adult centre at the Royal Liverpool Hospital.

Published on: 30 September, 2024

Dr Lynne Ball understood the position to be that products were supplied by the Royal Liverpool Adult Centre to Alder Hey.

Published on: 30 September, 2024

Dr Ball's recalled that, as a proportion of children registered per centre in the UK, Alder Hay "was one of the highest (if not the highest) proportion of HIV positive haemophiliacs."

Published on: 30 September, 2024

Data from UKHCDO suggested that 13 children were infected with HIV, a July 1987 report recorded 16 cases, and Dr Ball recollected approximately 12 boys who were HIV positive.

Published on: 30 September, 2024

By 1989, a large proportion of the clinical notes of children affected by HIV were missing essential treatment and decision-making details.

Published on: 30 September, 2024

There was no system of batch dedication to reduce donor exposure in Liverpool.

Published on: 30 September, 2024

Evidence confirmed that DDAVP was not in use until after 1988/89 in Liverpool. Dr Martin argued it was "of limited value, and difficult to use with small children."

Published on: 30 September, 2024

A report in July 1987 recorded 16 cases of children being infected at Alder Hey with HIV, though UKHCDO figures suggested 13 and Dr Ball recollected approximately 12.

Published on: 30 September, 2024

Annual Returns for Alder Hey Children's Hospital 1978 recorded the use of cryoprecipitate and both NHS and commercial concentrate.

Published on: 30 September, 2024

Annual Returns for Alder Hey Children's Hospital 1979 recorded the use of cryoprecipitate and both NHS and commercial concentrate.

Published on: 30 September, 2024

Annual Returns for Alder Hey Children's Hospital 1980 recorded the use of commercial concentrate (Factorate) increased.

Published on: 30 September, 2024

Annual Returns for Alder Hey Children's Hospital 1981 recorded Alder Hey treated its haemophilia patients almost exclusively with concentrate (both NHS and Factorate).

Published on: 30 September, 2024

Annual Returns for Alder Hey Children's Hospital 1982 recorded Alder Hey used almost exclusively concentrate, most of which was commercial.

Published on: 30 September, 2024

Annual Returns for Alder Hey Children's Hospital for 1983 recorded the almost exclusive use of concentrate, which was mostly Factorate.

Published on: 30 September, 2024

In 1984 Alder Hey treated its Haemophilia A patients only with concentrates, both commercial and NHS.

Published on: 30 September, 2024

In 1986 Alder Hey treated its Haemophilia A patients only with factor concentrate.

Published on: 30 September, 2024

Dr Savidge's report in 1992 revealed that Stephen, at the age of two years old, was treated with US commercial concentrates on 32 occasions in the course of 1982. He was treated with US commercial concentrates repeatedly again in 1983 and 1984, including as late as December 1984.

Published on: 30 September, 2024

Dr Savidge continues in his report stating Stephen twice received unheated US concentrates in early 1985.

Published on: 30 September, 2024

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