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The Lancet reported a data case of AIDS in a person with haemophilia who had received intensive treatment with Factor 8 concentrate of US origin.

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At a meeting of the haemophilia reference centre directors regarding communication between the CDSC, Dr Craske and haemophilia centre directors, Dr Galbraith was somewhat concerned that he had not heard about the Bristol case until after the patient's death.

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A letter from Dr Wassef outlined the symptoms of a haemophilia patient, stating that clinically he exhibited some of the stigmata of AIDS.

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In his statement to the Inquiry, Joseph Peaty questioned why Dr Wassef, a doctor who he and his mother trusted, had reassured his mother about the safety of the treatment he was receiving while knowing there were issues the entire time.

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Dr Wassef informed Dr Morag Chisholm at Southampton Hospital in a letter that a pupil exhibited some of the stigmata of AIDS.

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Dr Wassef informed a pupil's home clinician that clinically he exhibited one of the stigmata of AIDS in that he had lost 3kg in body weight.

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In an end-of-term letter to a pupil's home clinician, Dr Wassef said that the pupil did not exhibit the stigmata of AIDS apart from that he had lost 5kg in weight and had enlarged lymph nodes.

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In a letter to Dr Chalmers, Dr Wassef confirmed AIDS investigations were being undertaken on a pupil, that he exhibited no stigmata of AIDS apart from losing 2kg in weight and that they had undertaken AIDS-related tests.

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An article on AIDS in West Germany by L'Age-stehr et al confirmed that at least one patient with haemophilia had contracted AIDS and died in 1982.

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The Council of Europe's committee of experts on blood transfusion and immunology meeting in Lisbon produced a report which showed that there were two German patients with haemophilia who had contracted AIDS.

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The Council of Europe's committee of experts on blood transfusion and immunology report showed that Spain had reported three cases in people with haemophilia, two in Germany, one suspected case in Austria, and one suspected in Finland, retrospectively, after the person's death.

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Dr Liddel, the registrar in haematology, wrote after seeing one of Dr Bloom's patients, a 47-year-old man with severe haemophilia, that the patient was concerned about the possibility of acquired immunodeficiency syndrome.

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A patient registered that he was concerned about AIDS to Dr Bloom's staff and the registrar noted it was because the patient was well read, although they acknowledged that they credited it as a reasonable possibility.

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Haemophilia Treatment Policy Guidance stated to try to avoid using commercial factor concentrates and those who had never been given commercial concentrates should receive only NHS concentrates where concentrates were needed to limit exposure to risk.

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Policy guidance for the treatment of haemophilia patients was issued at the Cardiff Haemophilia Centre. The guidance advised using DDVAP, cryoprecipitate and only NHS factor concentrates for children and those with mild haemophilia.

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Professor Bloom suggested tests be performed to identify whether patients at the Cardiff Haemophilia Centre may have contracted illnesses.

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It was already known that a number of people with haemophilia who had been infected had begun to make claims, though Department of Health information about the cases was limited.

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A group action was contemplated by the plaintiffs and it was at this same time that the Department of Health informed ministers.

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Charles Dobson prepared a submission for the Minister of State for Health, David Mellor, that informed ministers of the legal action and to seek their views on resisting the case.

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Dr Andrzej Rejman was a senior medical officer in the Department of Health during this period.

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