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At a meeting of the Reference Centre Directors it was agreed that for young children, and those who were newly diagnosed with haemophilia, cryoprecipitate was to be used. Next preference was to be given to NHS factor concentrate.

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At a meeting of the CSM(B), it was stated that clotting concentrates were "life-saving" for haemophiliacs and the risk of AIDs was considered small. It was concluded that withdrawal of clotting factor concentrates from the market was not feasible on the grounds of supply.

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A hierarchy of safety used by the UKHCDO was implemented meaning that for those newly diagnosed with haemophilia, cryoprecipitate was used. Preference was then given to NHS Factor concentrate with US Factor concentrate given as a last resort.

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Dr Biggs stated that "Cryoprecipitate is a simple concentrate made from plasma at all Regional Transfusion Centres. Cryoprecipitate is much superior to plasma for the treatment of haemophilia A patients but the material is very variable from one sample to another and the potency cannot be known before it is used. For each dose the assumption must be made that the material is of low potency thus there is a tendency to use more material for each patient than is probably needed."

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Donations were tested for HTLV-3 at Oxford from this date with a temporal scope of six (rather than the national standard of five) years.

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Dr Craske expressed concern that he did not know the outcome of patients who had received Factor VIII from batch HL3186 and other batches which might have contained HIV.

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Four blood donations by a donor who showed symptoms of AIDS were identified.

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Recall arrangements in respect of batch HL3186 were instituted in Cardiff.

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The Blood Products Laboratory requested a lookback in relation to some batches of Factor 8. Dr Jayaswal, consultant haematologist at Wessex RTC, advised "Logistically it is going to be impossible for us to scrutinize 1500 donors from so long ago".

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Dr Lane of the Blood Products Laboratory chased a lookback exercise involving Wessex RTC and highlighted that the Factor 8 batches related to a potential HIV seroconversion in a young person with haemophilia.

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Dr Smith agreed to check the records at Wessex RTC to see if any HIV 1 antibody positive donors were implicated in batch 8CRV1526.

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Dr Gunson reported to a meeting of the regional transfusion directors on the plan to be adopted when a patient was diagnosed with AIDS and had donated or received blood or blood products.

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The terms of reference for the Advisory Committee on the National Blood Transfusion Service Working Group on AIDS were "To consider the implications for the National Blood Transfusion Service of testing blood donations for antibody to HTLV III and to report."

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During a meeting of regional transfusion directors it was noted that when tracing the recipients of donations from a HIV-positive donor, finding that a recipient had died was "not necessarily the end of the story" as the recipient's organs may have been used for transplantation.

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The working party of the Regional Transfusion Directors' Committee produced a report on the screening of blood donations for anti-HTLV-3 in regional blood transfusion centres. Procedures for testing donations were set out in full as well as the follow-up for HTLV-3 positive donations.

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It was agreed at a meeting of the Expert Advisory Group on AIDS sub-group that where long-standing donors were found to be antibody positive, only physicians should be informed (via the haematologist). It would be for the physician to decide further action. This line would be presented to the Expert Advisory Group on AIDS.

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A retrospective study of HIV infection associated with unheated NHS Factor 8 and 9 was produced.

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Dr Terence Snape produced a report on the recall of Factor 8 batch HL3186 occasioned by probable diagnosis of AIDS in a contributing donor.

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The meeting of the Expert Advisory Group on AIDS was briefed that funding proposals had been submitted for an extra 1,500 places on counselling courses at St Mary's, Birmingham and Manchester in the next financial year.

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The Expert Advisory Group on AIDS Screening Test Sub-Group met. The meeting focused on issues of testing and consent. It was noted that all individuals with positive results "must be told because of the dangers to their health and that of others".

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