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In 1981, a trial of shift working was conducted at Edinburgh and it was determined that the CSVM system was capable of continuous operation for periods of at least 120 hours.

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A memo from Dr Archibald McIntyre to Angus Macpherson examined further consideration the possibility that PFC might make a contribution to the supply of factor concentrates in the UK.

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Within "Notes on Feasibility Exercise Performed at Protein Fractionation Centre Liberton" it was stated instead of examining three-shift working patterns, the trial involved two shifts, each of 12 hours.

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Angus MacPherson wrote a letter to John Harley outlining that the necessary building works could be completed in approximately two and a half years.

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Within a Blood Products Laboratory report it was explained if PFC processed plasma to produce Factor 8 for England, then less would be needed to be spent on BPL.

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Professor Tuddenham commented on a legal opinion to the Haemophilia Society, writing "Would the provision of home produced concentrate have reduced the number of HIV infected patients? The answer here must very clearly be 'yes'".

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Professor Michael Makris advised within his witness statement to the Inquiry that he believed that, had the UK been self-sufficient in concentrates, the number of HIV infections in haemophilia patients would have been a lot less.

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Within the minutes of a UK Haemophilia Centre directors meeting it was described by Dr Mayne as limited quantities of concentrate from Elstree and Oxford.

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A statement from an investigative reporter investigating Belize's trade in plasma to the US described how a visitor to his motel room told him to take the first plane out the following morning. He left the next day.

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Cohn fractionation offered a way of separating blood into its constituent parts, and opened the possibility of using that part which was responsible for helping blood to clot without the far greater volume of blood from which it was separated.

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A lack of close oversight by the DHSS contributed to delays and expense in the redevelopment of BPL.

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Dr Maycock probably told the Chief Medical Officer that production facilities were not designed for the task nor large enough.

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A forward-looking interest was taken to updating and renewing production facilities.

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Additional major investment was needed in the UK if self-sufficiency was to be achieved.

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Inflation had exceeded 20% in 1975; and GDP had declined in both 1973 and 1975. Unemployment had peaked in 1976 at 1.5 million.

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Public expenditure increased in 1978-79.

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Oxford was known to provide a greater quantity of clotting factors than most if not all of the other centres at the time.

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Figure for the annual consumption of Factor 8 in the UK 23 August 1999.

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Figure showing annual consumption of CFC 1976 to 1994.

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Dr Walford understood from her visit to PFC that Liberton had a substantial capacity for expansion notwithstanding substantial staffing difficulties.

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