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The setting up of a Joint Steering Committee on Blood Products Production was precipitated by the grant of product licences to two commercial firms "which might entail large sums being spent by NHS authorities on these products."

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The Scottish CMO, Sir John Brotherson, wrote from Scotland offering further support for blood product production capabilities south of the border.

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It had been decided that 1,000 litres of fresh or fresh frozen plasma could be processed weekly by PFC, using pools of eight litres. This size of pool could be handled conveniently and quickly and was supported by clinicians using the material.

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It was considered that, as there was only a small possibility of expansion at Elstree, Edinburgh should be prepared to cope with the requirements of a larger part of England than originally intended so that the total growth of requirement could be handled by the two Blood Products Units. Dr Maycock considered that this approach to long-term planning was the only correct procedure.

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Dr Maycock indicated that he expected one third of the plasma from England would be processed at Liberton.

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At the end of December 1969 it was known to be unlikely that the Protein Fractionation Centre would begin production before the second half of 1973.

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Treasury approval was given to a final cost limit of £1,728,079 for the work on the Protein Fractionation Centre.

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The Expert Group on the Treatment of Haemophilia emphasised the importance of taking a UK view of provision for haemophilia therapy.

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At the minimum level of working, it was expected that 1,000 litres of plasma would come from Scotland each week, and the remaining 500 litres would come from England. John Watt questioned how this would work since there was no available plasma in England available at that time.

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The Scottish Home Health Department asked the DHSS when the Protein Fractionation Centre would be provided with English plasma for fractionation.

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It was reported at a DHSS meeting that the Minister of State stressed the need for cooperation between Scotland and England in manufacturing blood products.

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It was agreed at a SNBTS meeting that no start should be made on the large-scale processing of plasma from England and Wales until a plan had been agreed by transfusion directors.

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Transfusion directors agreed at an SNBTS meeting that Mr Watt could process a limited amount of plasma from BPL to establish yield and costs.

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It was agreed that Scotland should provide its own supply of fractions before undertaking work for the NBTS in England.

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John Watt, of the Scottish National Blood Transfusion Service, reported to the DHSS that a fifth of stored plasma had been processed.

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Dr Maycock wrote to the DHSS to tell them 25,000 litres of plasma per year would be available for fractionation by PFC, to begin in the autumn.

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Dr Maycock estimated BPL/PFL's contribution was 17.5 million international units per annum for England.

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SHHD said that it should be prepared for the PFC to be accepted as a pharmaceutical factory-type development.

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Within a letter from David Stevenson to A Eason a possible solution was proposed regarding the problem of securing an agreement acceptable to the workforce if asked to run a 24-hour shift system.

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A letter from Alec Parrott to Susan Maunsel stated that "even if all the difficulties in shift working at Liberton could be overcome tomorrow, it would not be regarded as sensible policy to put all our eggs in the Scottish basket as the planners appear to have originally intended."

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