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Dr Smith wrote to Dr Fowler, stating that it would be advisable to consider the problem of AIDS and blood products at the next meeting of the CSM(B) and asking Dr Fowler to produce a brief paper for the meeting.

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During oral evidence to the Infected Blood Inquiry, Dr Diana Walford stated that it was "a fairly unusual format" to have conclusions already made within an agenda for a committee meeting. This was in reference to an agenda for the Committee on Safety of Medicines Sub-Committee on Biological Products on 13 July 1983.

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During oral evidence to the Infected Blood Inquiry Dr Walford was questioned in relation to concentrates and the UKHDO's stance on the risk they carried. In response to the level of risk she stated that "the risk as they [UKHCDO] were defining it was what they perceived as the risk at the present time".

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Dr Fowler seemed to think it questionable that factor concentrates posed any additional risk to people with haemophilia. He asked in it whether haemophilic AIDS might be a function of the concentrate itself, but then said: "one cannot ignore other views and hope the problem will go away."

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Cutter - in a letter - to Dr Fowler, stated that the facts about AIDS were "very limited" and it therefore "can only be an assumption that AIDS can be transmitted by certain blood products." They added that "Also it is unclear whether the syndrome contracted by hemophiliacs really is the same as the AIDS syndrome contracted by other high risk groups."

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Dr Walford was clear that the medical stream of the civil servants of the DHSS believed that the likeliest cause of AIDS was an infective agent.

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The CSM(B) held a meeting on 13 July 1983 where Dr Smith stated that the material those attending received was confidential and should not be disclosed outside the meeting.

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Dr Bruce Evatt described the AIDS epidemic as evolving at "a frightening pace...The incidence rate has been increasing in hemophiliacs and the epidemic curve paralays [sic] that of the total epidemic curve."

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The CSM(B) discussed the possibility of withdrawing US preparations. It was concluded that this was not feasible on the grounds of supply. Moreover, the perceived level of risk did not "at present justify serious consideration of such a solution".

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Sonnabend et al stated in a journal article that the bombardment of recipients of blood products by a large range of different proteins, recognised by recipients' immune systems as "foreign" and consequently provoking an immune reaction, eventually overloaded the immune system of the recipient to the point that it failed.

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The CSM(B) stated that "the perceived level of risk" did not justify a "serious consideration" of withdrawing USA products from the UK Market. In addition it was not feasible on the grounds of supply.

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Dr Walford said she did not know the replacement of concentrates with cryoprecipitate was not feasible.

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Dr Lane produced a report on Acquired Immune Deficiency Syndrome for the CBLA on 22 April 1983.

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Sir Joseph Smith stated in 1983 that he was sure UK self-sufficiency was expected soon.

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Cutter learned that the French were offered heat-treated product by Hyland and Behringwerke earlier in 1983. As a result the French had stopped all imports "until they can evaluate the information and offers they have received insofar as they relate to the hepatitis and AIDS questions."

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Professor Christopher Bartlett in his written statement to the Archer Inquiry, referring to Dr Galbraith's letter and paper of the 9 May 1983, explained that Dr Galbraith had sought his opinion on the final drafts and that he fully concurred with the conclusions and advice he had expressed.

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Professor Stephen Palmer was appointed as PHLS CDSC's first medical consultant epidemiologist for Wales.

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Professor Stephen Palmer noted that Dr Galbraith was sick and not present for the CDSC in mid 1983.

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Dr Galbraith's colleague stated that he was off work for six weeks due to severe arthritis.

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The Council of Europe recommended the governments of member states to take all necessary steps and measures in relation to AIDS,mainly to avoid use of coagulation factor products prepared from large plasma pools.

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