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Dr Lane sent a letter to Mr Harley of the DHSS enclosing a paper titled "Reviewed Interim Budget Submission 1980/81, Capital Forecast Expenditure".

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A meeting was held to discuss expenditure on the upgrading of BPL. It was determined that proposals would be put forward on the basis that only £500,000 was available to spend on short-term developments at BPL.

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Dr Vaughan finally approved a submission that had been put to him proposing expenditure of £1.3 million over two years.

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Peter Wormald noted in a memo that the success of the extra expenditure would depend on persuading RHAs to increase plasma supplies.

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Long-term upgrading was considered at a meeting of the Scientific and Technical Committee.

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It was reported to the Committee that officials had been instructed by ministers to investigate the possibility of collaborating with private industry. Initial discussions had taken place.

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Worries were expressed on various aspects of collaboration with private industry, including the fear it would be difficult to prevent the contamination of UK material with imported Hepatitis viruses.

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In a DHSS press release, Dr Vaughan announced there would be no commercial management of BPL as there was a modernisation programme already underway.

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Dr Dunhill, a member of the Scientific and Technical Committee, wrote to Dr Vaughan outlining his acceptance of the situation in the short term only from consideration of the need to maintain plasma fraction supply.

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A minister asked the Policy Steering Group for the development of BPL to give consideration to the use of an existing factory which could be adapted at a relatively low cost to meet requirements.

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Approval was sought for planning to proceed on the assumption that BPL would process all the plasma for both England and Wales as the PFC did not have additional capacity without introducing three shift patterns.

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The Treasury approved the redevelopment in principle and agreed that the project should be fast-tracked.

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In a report, Dr Lane outlined that the final cost of MARP01 would be £2.8 million.

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Construction of BPL finally began in May 1983. The original completion date was to be July 1985.

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In a written answer on the NBTS and Factor 8, Kenneth Clarke, the Minister of State for Health, stated that "We decided in 1982 that this country should become self-sufficient in blood products".

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Lord Owen's reaction to Kenneth Clarke's words on self-sufficiency, in his written statement to the Inquiry, was that it was "extremely odd" and "as if the previous Labour Government programme had never existed".

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Lord Fowler noted in his evidence to the Inquiry that ministers invested money at a very considerable level, especially given the financial pressures on health spending. It was given priority at the expense of other pressing matters.

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Considering the evidence, there was always likely to be sufficient cryoprecipitate capable of being produced. However, clinicians, and no doubt many patients too, wished for the added advantages which factor concentrates offered, particularly in terms of home therapy.

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In wartime planning, two main plants were to process plasma for the UK: one south, one north.

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Dr Cumming was an enthusiastic advocate of forward planning when it came to plasma production.

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