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Individual clinicians, gay rights groups, and the National Hemophilia Foundation all joined calls at various stages to obtain more information before taking steps or "stigmatising" donors or users of blood products.

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The California Morbidity and Mortality Weekly Report confirmed that the three people with haemophilia whose cases had been reported in July 1982 had all died

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During a Centers for Disease Control (CDC) meeting, Dr Francis slammed his fist on the table and asked in effect how many AIDS cases, or how many deaths, would be needed before those attending took action.

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In the 1997 Krever Report Mr Justice Krever summarised the Centers for Disease Control (CDC) meeting of January 1983 by noting "there was no consensus on the question whether AIDS was caused by a transmissible agent, on the risk of AIDS from blood donations, or on the desirability of introducing new methods of donor screening or testing to reduce the risk of transmission."

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Recommendations were announced by the US Public Health Service on 4 March 1983, when their principles were endorsed by the American Red Cross, the American Association of Blood Banks, and the Council of Community Blood Centers.

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The US Public Health Service announced recommendations for the prevention of AIDS in patients with haemophilia and for other recipients of blood and blood products so that a uniform set of recommendations might be developed.

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Documents recorded that it was estimated that prison plasma accounted for approximately 2% of the total plasma collected in the US as of mid 1982 and was obtained from no more than six to eight centres.

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Dr Clyde McAuley, Alpha's medical director, was quoted as saying "So long as there is any question about the involvement of blood products, Alpha is taking all possible steps to reduce the potential risk for the hemophiliac receiving our factor VIII and factor IX concentrates."

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By the summer of 1983, 800 potential donors had "voluntarily disqualified themselves from the pool."

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Alpha's insistence on the measures taken pertaining to high-risk donors meant that they lost contracts with some blood banks that sold recovered plasma as they were not prepared to implement them.

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The American Blood Association made a public statement accepting that the cases of AIDS in people with haemophilia "suggest that AIDS may be of infectious etiology" and the organisation urged that "steps be taken as soon as possible to screen plasma donors to minimize the possibility of transmitting AIDS."

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Anti-HBc testing came to be regarded, and argued over, as the most likely surrogate test as the epidemiological pattern of AIDS was considered to be similar to that of Hepatitis B.

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Recommendations by the National Hemophilia Foundation's Medical and Scientific Advisory Committee were for the "Evaluation and implementation (if verified) of surrogate laboratory tests that would identify individuals at high risk of AIDS transmission."

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Dr Ojala of Cutter sent a memo to Whilhelm Schaeffler noting that the time had come for hepatitis core anti-body testing for plasma.

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The Hepatitis B Core Antibody Testing Group published an interim report in March 1984 and a full report in July 1984, and deemed that testing was not necessary.

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Of the 11 Biological Management Committee members, 3 voted in favour of anti-HBc testing, 1 abstained and 7 voted against it.

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Cutter introduced its own programme of mandatory anti-HBc surrogate testing.

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Biological Management Committee members outlined the perceived advantages and disadvantages of anti-HBc testing in a meeting.

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Alpha's AIDS Task Force considered what to do with 11 plasma donations from a donor in Dallas who "possibly" had "some AIDS symptoms". The task force decided to release four lots of factor concentrate containing his plasma but not to use any plasma from the donor that had not yet been pooled.

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Cutter stated that while it had not had to make any decisions about the disposition of a lot of Koate from a donor who developed AIDS, any decision would subsequently depend on a number of factors.

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