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1977 saw an increase in the volume of NHS concentrate used at the Manchester Royal Infirmary, but a greater volume of commercial as well.

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In 1978, NHS concentrate was used in greatest measure at the Manchester Royal Infirmary, but significant quantities of commercial concentrates and cryoprecipitate were also used.

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In 1979, NHS concentrate was used in the greatest measure at the Manchester Royal Infirmary but with large quantities of commercial concentrates and cryoprecipitate all used as well.

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It was observed that usage of cryoprecipitate in the North West region remained high in comparison with the national position, due to the policies adopted by the regional haemophilia service.

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Dr Wensley recorded that the NHS concentrate compared well with commercial. and that he was gradually changing his home treatment patients from commercial to NHS concentrate, with the plan that commercial concentrate would then be used only in operations.

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Dr Wensley reported that certain batches of Factor VIII concentrate had failed to comply with the new B.P. limit.

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Dr Gunson stated that Dr Wensley "worked very hard and devised a semi-automated method for producing high quality cryoprecipitate from which the patients in the region derived considerable benefit."

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Dr Delamore identified the incidence of hepatitis in haemophilia as being the highest priority in a March 1977 letter to Dr Rizza.

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An AIDS information leaflet was determined to be in the best interests of public health, despite potential sensitivity relating to homosexuals. Ministers were asked to agree to the funding and publication.

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Information was provided regarding the introduction of an information leaflet on AIDS by the BTS. This information encouraged the self exclusion of high risk donors.

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The draft information on AIDS leaflet stated that AIDS could "Almost certainly" be transmitted through blood and blood products.

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Lord Glenarthur was provided with a paper on AIDS prepared by Dr Walford.

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Information page on AIDS prepared by Dr Walford outlined the background and up-to-date position.

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Dr Malcolm Harris advised Dr Hunt and Jane McKessack to make the details of the introduction of the AIDS screening test public in order to take presentational advantage of the extra funding for PHLS as well as stressing the importance attached to safeguarding the BTS. This approach was recommended as a safeguard in the event that a publicised case of AIDS attributable to infected blood occurred.

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Paul Winstanley expressed concerns regarding a lack of speed in addressing the risks of AIDS spread through blood transfusions.

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A letter from Dr Gunson to Dr Ronald Oliver outlined Kenneth Clarke's concern "that the issuing of the leaflet may be regarded as a panic measure by the Government and lead to resentment amongst donors and alarm amongst patients".

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A memo from John Parker to Dr Oliver outlined that the Minister of State did not want the AIDS leaflet to be distributed with call-up cards.

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Dr Oliver held the view that the AIDS leaflet should be sent out with the call-up cards.

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In a memorandum to Dr Oliver, John Bolitho expressed concern that Kenneth Clarke would be "very irritated" if they were not able to control the distribution of the AIDS leaflet.

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In a response to a comment from John Bolitho that the AIDS leaflet "cannot be seen as a leaflet which you read and then change your mind about giving blood", Dr Oliver responded that was "precisely what it is intended for".

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