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The New England Journal of Medicine published an article by Masur et al titled "An outbreak of community-acquired pneumocystis carinii pneumonia".

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The New England Journal of Medicine published an article by Durack titled "Opportunistic infections and Kaposi's sarcoma in homosexual men".

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Strategy caucuses of the plasma collection and manufacturing interests in advance of their meeting regulators, the CDC and others were to become a common occurrence.

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Dr Ojala's (Cutter) memo of a meeting on non-specific (surrogate) testing concluded: "In summary, the conclusion of this meeting was that the time had come for Hepatitis core anti-body testing for plasma. Implementation will probably be achieved during 1984 for the industry."

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Dr Ojala's (Cutter) memo of a meeting on non-specific (surrogate) testing stated: "The approval of our heat-treat submission, in conjunction with core-screened plasma could present us with a potent marketing advantage. We made no mention of our plans to the others."

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The New England Journal of Medicine published an article by Siegal et al titled "Severe Acquired Immunodeficiency in Male Homosexuals, Manifested by Chronic Perianal Ulcerative Herpes Simplex Lesions".

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Inquiry publishes financial report

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Rhys Brennan

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At an Association of Haematologists North East Thames Region Working Party in Haemophilia meeting, Dr Lane "projected utilisation of factor VIII concentrate to grow to 60M iu [international units] per annum over a ten-year period" but suggested "100M iu per annum" as a more realistic estimate to achieve self-sufficiency.

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It was apparent that the fractionation capacity in England would need significant expansion.

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A Working Party on Human Antihaemophilic Globulin meeting determined "As the HAHG [human antihaemophilic globulin] concentrate prepared from plasma pools of up to 30-40 litres in volume apparently carried a risk of transmitting serum hepatitis, it was considered inadvisable...to increase the plasma pool volume much above this size".

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There was an upward shift in estimates of future needs, though slighter on this occasion. Current demand for Factor 8 was probably in the region of 60 million international units but, if clinical freedom continued, it could reach 100 million international units per annum.

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Alec Parrott wrote a letter to Susan Maunsell proposing a solution to the problem of securing an agreement acceptable to the workforce if asked to run a 24- hour shift system.

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Dr Maycock published "Present Sources of Materials for Treatment of Haemophilia and Potential Future Sources" showing the limits of fractionation capacity contributing to blood product shortfall; in order to meet the preferred number of units of cryoprecipitate and factor concentrates, capacity would have to increase by 800L a week.

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An editorial in The British Medical Journal entitled "Blood Donors and the Transfusion Service" argued that the blood services were ill-equipped to do the job as a modern transfusion service, suggesting that the "shortage" of blood and therefore plasma, allowing entry to the UK of the products of pharmaceutical companies, was not a real shortage, but a consequence of poor administration, organisation and underfunding.

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Andrew Mitchell wrote a letter to Malcolm Widdup noting the SHHD's proposal that the new blood products unit "should operate on the continuous flow principle and should be designed to a workload of 1,500 litres of plasma per week; but it will be capable of adaptation, without substantial structural alterations, to operate at levels up to 3,000 litres per week should this become necessary".

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The discussion in the Expert Group on the Treatment of Haemophilia - in particular its belief that "with the extension of home treatment joint surgery etc the current target may represent no more than _ to _ of the amount of Factor VIII which may be required in 5 years time or less" - was reported to the Central Committee of the National Blood Transfusion Service.

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The special allocations appear to have become subsumed as a part of the standard regional allocations, revised "in the usual way" to take account of cost increases.

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The Expert Report to the Infected Blood Inquiry: Public Health and Administration was produced, providing some evidence of the constrained financial position of the UK during the 1970s.

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A booklet entitled "Notes on Transfusion" was issued by the DHSS, SHHD and the Welsh Office.

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