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Meeting of the UK Haemophilia Centre Directors was attended by Dr Walford, the medical officer. Topics discussed include: 1979 annual returns; reports of the Working Party on hepatitis and home treatment; and commercial Factor 8 concentrates.

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The proposal to set up the Advisory Committee on the Virological Safety of Blood was submitted to ministers.

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John Davies wrote to the Under-Secretary of State for Scotland, John Mackay, about the emerging issue of AIDS. He stated that "Blood Transfusion Directors in Scotland are very aware of the problem and have it under constant consideration."

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The Medicines Division's Inspection Action Group deemed the collection and use of blood from prisons and borstal institutions "highly questionable" due to the prevalence of homosexual activity in prisons, coupled with the growing unease about the incidence of AIDS among homosexuals.

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The Advisory Group on Testing for the Presence of Hepatitis B Surface Antigen, produced a draft of their second report. The appendix recommended not discontinuing blood collection in prisons, provided that all donations underwent one of the more sensitive tests, such as RPH or RIA.This appendix was not included in the final version of the report published in September 1975.

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In a Health Circular, the DHSS set out the functions of the haemophilia reference centres.

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Dr Obank from the DHSS attended the meeting of the Haemophilia Centre Directors where Dr Biggs delivered a short summary of a report on the incidence of jaundice.

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At a meeting of Haemophilia Centre Directors it was suggested that prophylactic and home treatment of Factor IX "to severely affected Christmas disease patients was beneficial. Regimes of weekly, fortnightly or even monthly administration had been tried with success". However, for the treatment of "classical" haemophilia (factor VIII deficiency), prophylactic and home therapy treatment "was more difficult". "It was felt that a controlled trial might be helpful.

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In a Haemophilia Directors' meeting,13 September 1982, a US report was discussed which stated, among other things, that "there was a remote possibility that commercial blood products had been involved." Dr Ludlam in his oral evidence told to the Inquiry that he could not defend the word "remote".

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While presenting at a symposium held during the 3rd meeting of the European and African Division of the International Society of Haemtology, Dr Rizza stated that the Directors of UK haemophilia centres were "involved in a very active programme of research, including a review of the incidence of hepatitis and factor VIII antibodies in haemophiliacs, a trial of prophylactic treatment, and a survey of home therapy."

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It was decided that the General Meeting of Haemophilia Centre Directors would be in two parts: a business meeting followed by a scientific session.

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Professor Bloom became chairman of the Reference Centre Directors following Professor Blackburn's retirement.

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It was unanimously agreed by the Reference Centre Directors that freeze-dried concentrates were the material of choice for home treatment.

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The Reference Centre Directors noted that Drs Dormandy and Delamore had patients on home treatment with cryoprecipitate. Professor Blackburn agreed to write to both doctors to recommend commercial freeze-dried concentrate.

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Regular meetings of the reference centre directors began.

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Professor Ingram told the reference centre directors that "he had taken advice from the Medical Defence Union about home therapy and the ruling was that if a policy taken by a doctor (e.g. to institute home therapy) were one which he honestly thought to be best for his patient then the Medical Defence Union would defend him. Another organisation thought that the patient introduced to home therapy should have the risks and advantages of home therapy carefully explained to him."

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The first meeting of the reference centre directors discussed difficulties concerning the use and supply of Factor 8.

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Reference centre directors discussed the question of taking part in TV programmes, noting that such programmes could distort facts and present biased views.

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Reference centre directors agreed that DHSS representatives who were invited to attend Haemophilia Reference Centre Directors meetings for specific purposes as observers should only receive that part of the minutes which referred to the items for which they had been invited to attend and to which they had made a contribution.

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Professor Tuddenham accepted in hindsight that the risk of factor concentrates transmitting blood-borne infections was not sufficiently appreciated.

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