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The Spongiform Encephalopathy Advisory Committee concluded that the position statement on research into a link between BSE and nvCJD should not create expectation of proof of causative, although a link had been made between the two.

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In the journal article titled "The same prion strain causes vCJD and BSE", it was stated that studies now strongly supported the hypothesis that vCJD was causally related to BSE.

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SEAC recommended that the NBA should take steps towards leucodepletion of blood as far as practicable, pending results of an assessment of the risk of transmitting vCJD by this means.

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The EU Committee on Proprietary Medicinal Products to which the UK had recommended a policy of recall if a plasma pool was found to have been made in part from a donation from someone who had subsequently developed vCJD, agreed there should be a recall and SEAC agreed the surveillance until would set up a procedure to report cases.

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Professor Will of NCJDRSU made an application to reconsider ethical approval for the TMER on the basis it was unethical not to do the study, because it might be the only mechanism of identifying transmission of vCJD through blood and blood products.

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The Lothian Research Ethics Committee reinstated approval for TMER on the basis that the decision whether to inform someone identified as at risk by the TMER was left to the appropriate health authority.

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Mr AN told the Inquiry of having to insist upon procedures being carried out in the face of unwillingness from clinicians, and of then being made to wait around until the end of the patient list before being seen.

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In the interim report on incident involving blood components and vCJD and the patient notification exercise, it was stated that the Department of Health asked the Health Protection Agency to take the lead in notifying people.

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Some sections of the framework document on management of possible exposure to CJD through medical procedures included establishing a confidential database without consent, estimates of the infectivity of blood components and plasma derivatives, and advice on the investigation and management of incidents involving blood, were "greyed out" as they had not yet been finalised.

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This Department of Health paper recalculated the risk of blood-borne transmission of vCJD.

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During 2005, following the diagnosis of vCJD in two more former donors, a further ten living recipients of implicated blood components had been notified and asked to take special public health precautions.

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In her written statement, Dr Miflin expressed that as a result of the difficulty in testing blood for vCJD, and as a result of the experience of HIV and HCV in the preceding decades, a precautionary approach was taken regarding the emergence of vCJD in the mid 1990s.

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In her written statement, Dr Hewitt stated that the strongly held views of those who supported notification of those possibly affected and those against might have led to erring on the side of not acting soon enough.

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In her written statement, Dr Angela Robinson described a shift in approach which she attributed to Dr Kenneth Calman: the concept of the 'precautionary principle' was introduced and at that stage they were doing enormous things at great cost which had not been done before.

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In the first Advisory Committee on Dangerous Pathogens Transmissible Spongiform Encephalopathy Risk Assessment Sub-Group meeting, it advised the Department of Health that the policy adopted thus far had largely been driven by the "'worst case' scenarios".

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The Prime Minister stated the Cabinet Office was appointing an expert group in order to acquire relevant knowledge to make informed decisions in response to the Inquiry's recommendations on compensation when the report was published.

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The Chief Secretary to the Treasury stated that she was pleased the interim payments "at least" had been paid.

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The Paymaster General stated the appointment of an expert group to help respond to the Inquiry's recommendations was moving forward.

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The Paymaster General, John Glen, was asked about progress being made on implementing the recommendations in the Second Interim Report. He stated he sensed the "palpable frustration" and was doing everything he could to move things forward.

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John Glen stated that with the interim payments made in 2022 the Government recognised the immediate and urgent needs of those "most severely impacted".

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