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There was no discernible change of approach in 1983 and 1984, the predominant treatment for the children at Royal Manchester Children's Hospital remained commercial concentrates, although NHS Factor 8 continued to be used as well.

Published on: 30 September, 2024

There was no discernible change of approach in 1983 and 1984, the predominant treatment for the children at RMCH remained commercial concentrates, although NHS Factor 8 continued to be used as well.

Published on: 30 September, 2024

In July 1983, Dr Aronstam wrote to Dr Evans which would have alerted him to the fact that Treloar's was undertaking AIDS related tests and looking for the stigmata of AIDS.

Published on: 30 September, 2024

It is not clear when heat-treated concentrates were introduced but as late as May 1985 it appears RMCH had not provided BPL with a list of named patients to receive heated NHS Factor 8.

Published on: 30 September, 2024

Dr Evans provided Dr Snape with a list of patients that he wanted to heat-treated Factor VIII and IX concentrates to use on a named patient basis.

Published on: 30 September, 2024

Dr Evans wrote an article in which he indicated that did not make any significant adjustments to his approach to treatment in response to the risk of AIDS.

Published on: 30 September, 2024

The Royal Manchester Childrens' Hospital produced a leaflet containing information on HIV for patients and their families, which stated it took a while for the risk of transmission from commercial concentrates to become known.

Published on: 30 September, 2024

In Belfast children with bleeding disorders were cared for at the Royal Belfast Hospital for Sick Children until around the age of 14, when they transferred to the haemophilia centre at the Royal Victoria Hospital.

Published on: 30 September, 2024

Dr Stanley Dempsey was the consultant paediatric haematologist at the Royal Belfast Hospital, taking over from Professor John Bridges.

Published on: 30 September, 2024

When Dr Dempsey began work as a haematologist at the Royal Belfast Hospital, non-A non-B Hepatitis was not thought sufficiently serious to merit withdrawal of commercial concentrates.

Published on: 30 September, 2024

At the DHSS meeting, Professor Hardisty noted that at Great Ormond Street Hospital the emphasis was on early treatment of minor bleeds in children to prevent crippling, that more treatments were being given per patient and that some 30% of 69 registered patients attended frequently or fairly often.

Published on: 30 September, 2024

By 1976 all Great Ormond Street Hospital patients on home treatment were receiving commercial Factor 8 concentrates, through a special allocation from the DHSS.

Published on: 30 September, 2024

Great Ormond Street Hospital complained of a shortfall of NHS concentrate and a need to purchase more commercial concentrates.

Published on: 30 September, 2024

At Great Ormond Street Hospital in 1976 there was substantial use of both cryoprecipitate and commercial concentrates, with very little NHS concentrate used.

Published on: 30 September, 2024

The amount of cryoprecipitate used by Great Ormond Street Hospital reduced in 1977, with some rise in NHS Factor 8 but treatment was predominantly with commercial concentrates.

Published on: 30 September, 2024

There was an increase in the use of cryoprecipitate and NHS factor at Great Ormond Street Hospital but most treatment (501,214 units) was with commercial concentrates (Factorate and Koate), for the treatment of 42 patients.

Published on: 30 September, 2024

463,441 units of Factorate were used at Great Ormond Street Hospital in 1979 (and a modest amount of Koate: 1,590 units), together with 159,675 units of NHS Factor 8 and 62,720 units of cryoprecipitate.

Published on: 30 September, 2024

432,326 units of Factorate were used at Great Ormond Street in 1980 (and 116,877 units of Kryobulin), together with 128,859 units of NHS Factor 8 and 22,890 units of cryoprecipitate.

Published on: 30 September, 2024

The mother of a child treated at GOSH, Della Ryness-Hirsch, protested when her son's treatment was changed from cryoprecipitate to Factor 8, but was told that there was not enough cryoprecipitate available and that NHS Factor 8 was perfectly safe.

Published on: 30 September, 2024

1,339,864 units of Factorate were used at Great Ormond Street Hospital in 1982 (and 35,599 units of Hemofil), together with 205,348 units of NHS Factor 8 and 18,620 units of cryoprecipitate.

Published on: 30 September, 2024

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