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At Great Ormond Street Hospital in 1983, there was increased use of NHS Factor 8, little use of cryoprecipitate, and the volume of Factorate fell substantially compared to the previous year.

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At Great Ormond Street Hospital in 1984 NHS Factor 8 concentrate was the blood product used the most. There was a significant reduction in the amount of commercial concentrate used.

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Professor Hardisty was added as an investigator to the Clinical Trial Exemption for Armour's heat-treated Factorate.

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Professor Hardisty indicated that he would like to switch to the heated NHS products for all patients, irrespective of their antibody status, as soon as supplies permitted.

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Great Ormond Street Hospital wrote to BPL, stating that many of the parents were very anxious about the use of commercial concentrate.

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Great Ormond Street Hospital was unable to locate any stored relevant documentation from the 1970s and 1980s (except individual patient records) to provide to the Inquiry, and there was no personal paperwork of Professor Hardisty's from the time to be found in storage.

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Dr Anna Pettigrew asserted in her statement to the Inquiry that the patients at Glasgow Yorkhill Haemophilia Centre would be transferred to Glasgow Royal Infirmary at 15-16.

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Dr Pettigrew noted that the commercial Factor VIII product was more 'user friendly' and dissolved more quickly than the SNBTS product.

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Minutes of the West Midlands Regional Health Authority Working Party on the Treatment of Haemophiliacs which agreed to recommend to Dr Ala, the regional transfusion director, that NHS concentrate should be distributed in proportion to the number of patients treated.

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Minutes of the West Midlands Regional Health Authority Working Party on the Treatment of Haemophiliacs where it was recommended that during the next 6 months all Centres should cut down on the use of Factor VIII and increase their usage of cryoprecipitate. Members agreed any shortfall would have to be met by increased purchasing of Commercial Factor VIII.

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Minutes of the West Midlands Regional Health Authority Working Party on the Treatment of Haemophiliacs where there was reported to be an excess of cryoprecipitate. This was potentially attributed to overstocking in anticipation of a reduced supply of Factor VIII concentrate from BPL.

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Dr Mounir Wassef wrote to Dr Hill, outlining that one of his patents was exhibiting AIDS stigmata.

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Medical Report and Opinion was prepared regarding the treatment of Jonathan Buggins by G. F. Savidge

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Dr Savidge stated the administration of a large donor pool of commercial material in preference to cryoprecipitate without authorisation was negligent.

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Dr Savidge stated Armour concentrate was used exclusively in 1983 and 1984 with no reference to the available NHS concentrate at the hospital.

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Dr Savidge noted Dr Hill's view that continued use of the same batch confined the risk of infectivity but it was not practised on Johnathan Buggins. Between 1981 and mid-1984, he had been exposed to 20 different batches of Armour factor VIII.

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A report was produced by Professor Ingram, no evidence was found of any consideration being given to prioritising the child for NHS concentrate, or that consideration should have been given to no product in the place of commercial product.

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New Scientist published an article which referred to the possibility of AIDS being spread through Factor 8 concentrates.

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Dr Hill downplayed the risk of getting AIDS from using Factor VIII concentrate compared to the risk of arthritis by not using it.

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West Midlands Regional Health Authority Working Party on the Treatment of Haemophiliacs supported the document prepared by the Reference Centres Directors on the effects of AIDS on the treatment of haemophiliacs.

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