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A protocol for a pilot study to assess the introduction of routine anti-HCV tests in RTCs was drafted in November 1989 and carried out by Dr Gunson.

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The minutes of the UK Advisory Committee on Transfusion Transmitted Diseases meeting noted the policy regarding anti-Hepatitis C testing and that the focus should be on providing counselling services for those found to be anti-HCV positive.

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The minutes of the UK Advisory Committee on Transfusion Transmitted Diseases meeting noted the ACVSB agreed the anti-HCV test was a major step forward in identifying those who could transmit the virus, but that routine screening should not commence until the FDA had granted a license and that a cost benefit appraisal should be conducted and discussed with the Department of Health.

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The minutes of the UK Advisory Committee on Transfusion Transmitted Diseases meeting noted that ACVSB had deferred the decision to introduce routine screening for blood donations until April 1990.

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The agenda for the UK ACTTD meeting included Hepatitis C lookback, but there was no discussion of this recorded in the meeting minutes.

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The minutes of the UK Advisory Committee on Transfusion Transmitted Diseases meeting did not discuss Hepatitis C lookback.

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Dr Jean-Pierre Allain sent a fax to Dr Gunson with a proposal for HCV testing study that supported identifying and approaching all recipients of blood that was "screen positive (repeat reactive)".

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In a memo to Dr Thomson and Dr Mary Brennan, Dr Contreras suggested that an application should be made "as soon as possible" to the Medical Research Council and/or the Wellcome Foundation for funding in order to undertake a lookback for recipients of blood "who are now confirmed positive for HCV antibodies."

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The minutes of the ACVSB meeting recorded concern that there would be "problems of counselling donors in view of the state of knowledge about the significance of a positive reaction to the test."

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Professor Cash, SNBTS, wrote to Dr Gunson, NBTS, seeking his view on HCV lookback. He wrote: "You will have noted that our team have indicated the need for a policy statement and in their view 'look-back' should be attempted."

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Professor Cash provided a letter to Dr Gunson about the impact of the Gulf conflict relating to HCV Lookback.

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Dr Harrison held the view that a lookback study was "too late".

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Dr Contreras described how there was insufficient time to obtain ethical approval at each hospital for a lookback study.

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In a meeting on national study on surrogate NANBH markers in blood donors, it was agreed there would be no attempt to follow up on the recipients of surrogate marker positive donations.

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Dr Geoffrey Dusheiko advocated for obtaining a research grant "for [the] potentially clinically beneficial undertaking" of considering the value of treatment by interferon and ribavirin.

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The SACTTI meeting found that a "major limiting factor to completion of the look-back" was the unavailability of medical records.

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Medical officers of the Ministry of Health published a memorandum in "The Lancet" about incidences of jaundice.

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A letter from Dr Mitchell to Professor Cash discussed whether the BTS should have a lookback policy so as to identify donors who may have transmitted non-A non-B Hepatitis.

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Professor Cash wrote to Dr Gunson to see if he would establish a UK BTS and lookback study as soon as possible.

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Dr Gunson spoke to Professor Allain who agreed to provide a protocol for a prospective lookback study.

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