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Only six regional health authorities had agreed to a plan to meet the self-sufficiency timescales.

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The Trent Regional Health Authority had to subsidise the collection of plasma to be supplied to BPL by £1.2 million.

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The cost to many RTCs in obtaining plasma exceeded what BPL would pay for it, as was the case in North East Thames region.

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Yorkshire estimated that it cost them £15 more per kg to supply plasma to BPL than they received.

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It cost Yorkshire £18.50 more per litre to supply plasma to BPL than they received.

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The Department of Health set the cost BPL paid the RTCs for plasma without reference to the actual cost to the RTCs of collecting that plasma.

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Dr Robinson noted that the price for a unit of apheresis plasma proved to be insufficient to cover the cost of producing it at the Yorkshire RTC.

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While the pro rata system was in place, the region served by the Yorkshire RTC was self-sufficient in Factor 8 due to having made use of plasmapheresis to produce sufficient plasma.

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In 1975, 90% of transfusions in England and Wales were of whole blood and 10% red cell concentrates; by 1985 around 50% of blood issued for transfusion consisted of the red cell component.

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The East Anglian RTC was still issuing as much as 40% of the blood it issued as whole blood.

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The Oxford RTC had proposed to use 45,000 SAG-M packs but this was reduced by their RHA.

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The Trent RTC considered reducing the amount of plasma it was going to send to BPL "since both P.P.F. and Factor VIII would be produced at a level greater than for regional needs".

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RTCs in the Northern area could not get funding for SAG-M.

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Despite having a target of 11,800kg in plasma production, the Welsh RTC reported that it was unlikely to receive finance to cover SAG-M, so would probably only reach 9,000kg.

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In a report to the CBLA, Dr Gunson stated that there had been difficulties obtaining funds from RHAs and several regional transfusion directors had cancelled orders of SAG-M packs.

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Dame Contreras gave evidence to the Inquiry that the Edgware North London Centre had a donor association which organised awards ceremonies every month to celebrate donors who had reached milestone numbers of donations.

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The North West Thames RTC experienced blood shortages, despite Professor Contreras stating the centre was collecting "more than anybody else per thousand population".

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The number of regular attenders at the North London RTC exceeded 2,500, and over 80% of these donors attended for donation once a fortnight.

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At the North London Blood Transfusion Centre, Edgware, the first unpaid volunteers began donating by plasmapheresis.

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Dr Harrison did not consider plasmapheresis to be an efficient way to collect plasma.

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