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In December 1979, the Haemophilia Working Party met and discussed the fact that up to 70% of patients with severe haemophilia had abnormal liver function tests, with a wide spectrum of histological abnormalities.

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In 1970, at the haemophilia centre at Leeds, based at St James's University Hospital Dr Layinka Swinburne was the director and in 1985, she was joined by Dr Bernard McVerry.

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By 1977 the haemophilia centre at Leeds, based at St James's University Hospital were using a substantial amount of commercial concentrates.

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The haemophilia centre at Leeds, based at St James's University Hospital showed no evidence of batch dedication or evidence of risk reduction.

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In 1978 at the haemophilia centre at Leeds, based at St James's University Hospital very little cryoprecipitate was in use.

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In 1979 at the haemophilia centre at Leeds, based at St James's University Hospital there was no cryoprecipitate was in use.

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The haemophilia centre at Leeds, based at St James's University Hospital showed that by 1977, was using a substantial volume of commercial concentrate.

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Dr Bevan described how, in 1978, there was a limited amount of risk management that took place during that period.

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Commenting on the reaction to AIDS and the risk of transmission, Dr Bevan held that during the period around 1983, that the general attitude of doctors was not to alarm the public as there was no conclusive proof.

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During March 1983, a meeting was held, by the Haemostasis Club, where clinicians met to discuss and hold presentations that were topical to the medical field.

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Dr Bevan held the opinion that he did not understand why both UKHCDO and the reference centre directors were so slow to recognise and react to the risks of AIDS being transmitted to their patients and how he felt that it was a denial of the reality.

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Dr Bevan described how at St George's Hospital, during the late 1970s and early 1980s, that there was a move from cryoprecipitate and towards commercial concentrate.

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Dr Bevan described how at St George's Hospital, during the late 1970s and early 1980s recalled that there was a growing demand for home treatment, especially in children and young people.

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Dr Bevan described a meeting with Professor Flute during 1985 where Professor Flute stated that AIDS was in no way a proven infection.

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Dr Bevan described a meeting with Professor Flute during 1985 where Professor Flute stated that no action with regards to changing the infusion practice in haemophilia would be taken unless there was firm guidance from UKHCDO.

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Dr Bevan stated in oral evidence that there was no AIDS Advisory Document until December 1984.

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Dr Bevan recalled that at St George's hospital in the 1980s there were between 15 and 18 patients with HIV.

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Dr Bevan held that during the 1970s, the general assumption by medical professionals was that hepatitis was "an inconvenience, but essentially harmless"

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The haemophilia centre directors' annual meeting on 30 September 1980 included a discussion about the increasingly inadequate supplies of NHS factor VIII concentrate.

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In a meeting held by the haemophilia centre directors' annual meeting on 30 September 1980 Dr Craske stated that the use of small pooled concentrates would help reduce the risk of hepatitis in the haemophilic population

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