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Dr Craske explained that there was a "possibility" that transmission by blood and blood products may become "a serious problem" and that in the UK "widespread transmission could occur...unless precautions are taken to exclude donors from the already identified high risk group for AIDS".

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Dr Craske reported to the UKHCDO on the cases of AIDS in different parts of the world given. The number of cases in patients with hereditary disorders of blood coagulation had reached 21 in the USA. 7 cases in Europe had been reported, including two in the UK. Description of a recent study of 7 patients with AIDS associated with blood transfusion.

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Minutes from the meeting of UK Haemophilia Centre Directors where Professor Bloom stated the the UK was recognised throughout the world as having the best organisation for treatment of haemophilic patients and Dr Craske asked for special attention to be given to his report on HTLV III the importance of accurate incidence of HIV in the UK and a need for better reporting

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Appendix collated by Dr Craske containing graphs and histograms based on reports received by Haemophilia Centres on patients who received the same batches of blood products as the Cardiff and Bristol AIDS cases.

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Inquiry publishes expert report on Public Health and Administration

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Dr Lane in a letter to the reference centre directors stated that it was agreed that a meeting should be held "to discuss AIDS in relation to the management of haemophiliacs and the implications for treatment with factor VIII concentrates" and that 10 December was the first date suitable for the majority of participants.

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In a response to Dr Lane, Professor Bloom wrote that "clearly the matter is of great importance and has certainly come to a head with the Australian experience and with the unfortunate death of the Newcastle patient. I am only glad that we had decided in advance of these events to take some action"

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In a letter to Dr Lane, Dr Rizza suggested a number of questions which he thought needed to be considered at the meeting, including whether directors should now switch to using only heat-treated Factor 8 concentrates.

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Dr Lane produced an agenda for the meeting with the Haemophilia Centre Directors.

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In the US over 6,000 cases of AIDS were reported including 52 people with haemophilia and 102 cases in the UK with 3 reported in people with haemophilia.

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Professor Bloom wrote to Dr Ludlam seeking comments on his draft notes of Reference Centre Directors meeting on 14 December 1984.

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Professor Bloom wrote to Dr Lane seeking comments on his draft notes of Reference Centre Directors meeting on 14 December 1984.

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UKHCDO's AIDS Group was told that the Haemophilia Reference Centre AIDS Advisory Document dated 14 December 1984 was sent to all haemophilia centres in the UK.

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UKHCDO's AIDS Group heard a difference of opinion with regard to Factor 9. "Some Centres had stopped using NHS factor IX and were now using heated commercial factor IX while others intended to continue for the meantime with the unheated NHS factor IX."

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Annual return for 1983 shows Frimley Park Haemophilia Centre treated 4 Haemophilia A patients and 1 von Willebrand's disease patient that year.

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Dr Dempsey stated that there was "resistance among the haemophilia treaters about the significance of concentrate and the emerging AIDS problem."

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Dr Dempsey commented that he had "no major doubt" or "no real doubt" that AIDS was transmissible by blood or blood products "because any alternative theory didn't really seem to hold water"

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Dr Dempsey mentioned that the best decision would have been to go onto NHS material, as opposed to cryoprecipitate in the 1980s.

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After a child was admitted in 1981 following an accident where cryoprecipitate "failed to do the job that was asked of it on that occasion", Dr Dempsey's "confidence in cryoprecipitate" was shaken.

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In August 1980, cryoprecipitate was used "fairly exclusively" in the Royal Belfast Hospital for Sick Children haemophilia unit.

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