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First death from AIDS in the UK of a person with haemophilia.

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The British Medical Journal commented that there was no evidence that any factor product was free from the risk of transmitting AIDS.

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Dr Robert Gallo announced he had found the virus which caused AIDS.

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An article in The Observer described the risk of AIDS.

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Article in The Observer described risk of AIDS.

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A report of a study at the Lord Mayor Treloar College concluded that "As antibody is evidence of previous exposure to serum hepatitis, it probably also indicates immunity and it is not surprising that clinical hepatitis is uncommon in adult haemophiliacs".

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It was stated that Treloar's was the only establishment in the United Kingdom which could provide the opportunity and the facilities for extensive clinical trials of various kinds of treatment and that this type of research could not be conducted anywhere else.

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It was noted that a proposed tranexamic acid trial at Treloar's would have to be arranged so that it did not "interfere with any future trial of prophylactic therapy".

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It was noted at Treloars that "an attempt would be made to trace the source of infection in every instance of hepatitis however mild clinically."

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Dr Aronstam began collecting "in depth" data on every bleeding episode at the Treloar Haemophilia Centre having been appointed as director.

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A book titled "Haemophilic Bleeding: Early Management at Home", written by Dr. Aronstam, was published.

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Dr Aronstam reported that Treloars "had stopped recording the batch numbers of the transfusions because of the enormous amount of work this entailed".

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WHO recommended record keeping to help to control serum Hepatitis, including the batch numbers of blood products used for patients.

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It was reported that a minute fraction of a millilitre of virus-laden blood was sufficient to cause hepatitis. The production of large-pool plasma was abandoned as a result of this.

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Dr Biggs suggested that it was not yet proved that commercial Factor 8 was much more dangerous in causing hepatitis than other preparations.

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Dr Craske stated that NHS Concentrate was likely to be safer than commercial concentrate when it was available.

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Dr Arblaster stated several boys had withdrawn from the trial of prophylactic therapy with Factor 8 at Alton for various reasons.

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The second of three trials of prophylactic therapy at Treloar's studied twice weekly prophylactic therapy in Haemophilia A.

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The third of three trials of prophylactic therapy at Treloar's studied transfusion requirements of adolescents with severe Haemophilia A (1976-77)

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Dr Aronstam reported to the MRC that "We have now gone as far as we can with this trial, in the face of, I may say, enormous difficulties which I feel were a direct result of using a placebo for this study."'

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