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In 1983, it had become evident that the transmission of HIV through blood and blood products was likely.

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The 1984 AIDS donor leaflet introduced by the DHSS helped donors identify measures which would reduce infection.

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The MMWR reported that the epidemiology of AIDS suggested the involvement of an unidentified blood-borne agent. The CDC emphasised AIDS high mortality rate, the expectation that the mortality rate a few years after diagnosis might be far greater and the rapid increase in the reported incidence of AIDS.

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Dr Craske produced a paper on AIDS for the Medical Research Council ("MRC") Hepatitis Vaccine Working Group.

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An article stated that the spread of AIDS in people with haemophilia and children was possibly due to blood products and intimate family contact.

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When questioned regarding the previous warnings of the danger of contaminated blood supplies coming from the United States, the Prime Minister responded by stating that "We first need to find out a good deal more about the incident and the causes that have been reported before coming to any conclusion."

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Andy Burnham stated that "The duty of the state is to provide the best possible health care; the safest, highest quality health care - for the people of England. And to protect them from health risks."

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An article published in the Lancet, titled Acquired Immunodeficiency Syndrome, concluded that transmission through blood was likely.

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The Advisory Committee on Dangerous Pathogens was established in 1981.

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Dr Brian McClelland presented a draft leaflet in an SNBTS meeting. The South East Scotland RTC subsequently issued this leaflet in June 1983. It highlighted the potential infectious nature of AIDS, suggesting that the disease, thought to be caused by a virus, could be transmitted through blood products like Factor 8.

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In his letter to Dr Brian McClelland, Dr Cash proposed that the SNBTS Co-ordinating Group meeting on 30 August 1983 be
updated on the position with regard to a UK leaflet and agree on a method of distribution to donors.

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Dr Cash sent Dr Brian McClelland a draft donor leaflet on AIDS.

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At a CBLA meeting, Dr Bell proposed a study to identify high-risk donors for AIDS through HBc screening. Despite a lack of enthusiasm for the study, the Committee felt they needed to identify potential transmitters of AIDS.

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In a CBLA Central Committee for Research and Development meeting Dr Bell voiced concerns about the potential AIDS donor leaflet.

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Notes on directors meetings describe regular communication between the SHHD and DHSS.

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At an Advisory Committee on the NBTS meeting it was recommended that the DHSS ministers consider issuing the revised leaflet to discourage high-risk donors from donating.

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At an Advisory Committee on the NBTS meeting Dr Bell suggested using small donor pools so that the health status of donors could be more closely monitored.

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Dr Bell emphasised the need for a uniform policy throughout the UK.

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A memo from Hugh Morison to John Mackay stated that following the revised SNBTS leaflet, steps were now being urgently taken to issue the leaflet to donors in the West of Scotland and to those throughout Scotland who did not receive mailed reminders.

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A memo from Hugh Morison to John Mackay stated that following the discovery of HTLV-3 antibodies in Scottish people with haemophilia, there were steps being taken to withdraw implicated Factor 8.

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