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In the minutes of the 163rd regional transfusion directors' meeting, the chairman was recorded as saying that 90% of the plasma production for Factor 8 concentrate had already been achieved.

Published on: 30 August, 2024

In response to a parliamentary question, Roland Moyle stated that the production of Factor 8 estimated in 1975 was exceeded by July 1977 and production had risen substantially since then.

Published on: 30 August, 2024

In a note to Dr Maycock, Dr Ellis expressed that expansion to producing 25 million international units of Factor 8 per year would cause a serious overcrowding of facilities, unless some additional building work was done.

Published on: 30 August, 2024

In her evidence Dr Walford agreed that it was or should have been known to all those involved with BPL in the second half of the 1970s that the demand for blood products was rising, that it was or should have been obvious that BPL was outdated and too small, and that significant investment was required in order to be able to meet the rising demand, and that the Government had determined that BPL should meet standards equivalent to those expected of commercial plants.

Published on: 30 August, 2024

Dr Waiter wrote in a memo that in order to meet the anticipated demand for the principal plasma fractions, a new plant would have to be acquired. Plans for the future development of BPL had by this time been drawn up.

Published on: 30 August, 2024

Concerned with costs, the DHSS advised that there was no money available for either the stop-gap proposals or an upgrade of BPL.

Published on: 30 August, 2024

In a letter, J Brown advised Mr Williams that the Medicines Inspectorate report had highlighted the severe shortcomings of the standards at BPL and that had the laboratory not had Crown immunity activities would have been suspended immediately.

Published on: 30 August, 2024

John Harley wrote a memo that noted he had tried to dissuade the Scientific and Technical Committee from initiating planning as no decision had yet been taken to build a new fractionation plant at BPL and there was no budget for even a development plan.

Published on: 17 October, 2024

Dr Vaughan, then the Minister of State for Health, agreed to there being a short-term upgrade to BPL and further exploration of options for rebuilding within the NHS or in collaboration with industry.

Published on: 30 August, 2024

Ministers asked to see whether there might be scope for further savings in the stop-gap measures as they were concerned that there might be no justification to incur short-term costs on upgrading if BPL was to be rebuilt.

Published on: 30 August, 2024

Dr Lane sent a letter to Mr Harley of the DHSS enclosing a paper titled "Reviewed Interim Budget Submission 1980/81, Capital Forecast Expenditure".

Published on: 17 October, 2024

A meeting was held to discuss expenditure on the upgrading of BPL. It was determined that proposals would be put forward on the basis that only £500,000 was available to spend on short-term developments at BPL.

Published on: 25 October, 2024

Dr Vaughan finally approved a submission that had been put to him proposing expenditure of £1.3 million over two years.

Published on: 11 October, 2024

Peter Wormald noted in a memo that the success of the extra expenditure would depend on persuading RHAs to increase plasma supplies.

Published on: 30 August, 2024

Long-term upgrading was considered at a meeting of the Scientific and Technical Committee.

Published on: 30 August, 2024

It was reported to the Committee that officials had been instructed by ministers to investigate the possibility of collaborating with private industry. Initial discussions had taken place.

Published on: 30 August, 2024

Worries were expressed on various aspects of collaboration with private industry, including the fear it would be difficult to prevent the contamination of UK material with imported Hepatitis viruses.

Published on: 10 October, 2024

In a DHSS press release, Dr Vaughan announced there would be no commercial management of BPL as there was a modernisation programme already underway.

Published on: 17 October, 2024

Dr Dunhill, a member of the Scientific and Technical Committee, wrote to Dr Vaughan outlining his acceptance of the situation in the short term only from consideration of the need to maintain plasma fraction supply.

Published on: 30 August, 2024

A minister asked the Policy Steering Group for the development of BPL to give consideration to the use of an existing factory which could be adapted at a relatively low cost to meet requirements.

Published on: 30 August, 2024

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