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A fourth case of vCJD transmission was associated with blood transfusion and was reported to the press.

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It was confirmed that a post-mortem carried out on a man with haemophilia found the vCJD prion in his spleen. He did not die of vCJD; nor was it present in the brain. The probability was that he had been infected and that the likeliest cause was his treatment with plasma product.

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The CJD Incidents Panel wrote to those responsible for tracing vCJD-implicated plasma batches setting out tables of implicated batch numbers.

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A second case of transfusion-related vCJD was reported in July 2004.

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People with a bleeding disorder were informed by their haemophilia centre and given an opportunity to discuss the implications and to find out if they had received an implicated batch if they wished.

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Alan Milburn, Secretary of State for Health, announced further details of the compensation scheme.

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From the end of 1999, no UK plasma was used.

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The MSBT discussed how to manage donors known to have received blood from people who subsequently developed vCJD. The outcome was reported to Dr Angela Robinson in her role as medical director of the National Blood Authority.

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The Chief Medical Officer issued a statement which reported that three patients who had suffered from vCJD had been blood donors, and a fourth was suspected of having been one too.

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The Lothian Ethics Committee initially took the view that no attempt should be made to trace nor inform recipients of implicated donations, and after being asked to review its position in October 1997, reiterated its earlier advice.

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Dr Patricia Hewitt spoke informally to Professor Ian Kennedy regarding a study to check on recipients of those blood donors who later developed vCJD.

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The Coroner wrote to the Secretary of State for Health to express his concern that Mark Buckland had not been told of his being infected with vCJD earlier.

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Professor Collinge's team reported the development of a prototype blood test to diagnose vCJD in symptomatic individuals which could be further developed into a large-scale screening test for asymptomatic vCJD prion infections.

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Dr Will and others published an article in "The Lancet" regarding their findings pertaining to a new variant of CJD in the UK.

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The Department of Health made recombinant available to all children under 16 and new patients in England, matching what was already provided in Scotland, Wales and Northern Ireland.

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The MSBT agreed that any donor who had received a blood transfusion after 1 January 1980 should be excluded from donating.

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A summary of the inquest into the death of Mark Buckland was released.

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Caroline Flint responded on behalf of the Secretary of State for Health to the Coroner's letter regarding Mark Buckland not having been told of his situation earlier.

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Dr Patricia Hewitt, in her written statement to the Inquiry, explained that the initial decision not to inform recipients who had received vCJD was made by the Department of Health.

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From 1 April 1998 donors who had had brain surgery before August 1992 were permanently deferred.

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