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A World Health Organization Scientific Group report on viral hepatitis stated that the present techniques for detecting Hepatitis B antigen were thought capable of preventing up to 30% of post-transfusion hepatitis, which were deemed more sensitive than earlier techniques.

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The NHS advisory report on testing for Hepatitis B described the methods available for detecting HBsAg and anti-HBs and recommended that CIE should no longer be used and that regional transfusion centres should use either reverse passive haemagglutination or radioimmunoassay.

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Dr Rosemary Biggs predicted that within the next two years very large amounts of commercial products would become available in the US, and the UK would be obliged to purchase them at a high cost if it did not make urgent plans to meet its domestic demand.

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Dr Garrott Allen found that prison blood accounted for 90% of post-transfusion icteric hepatitis.

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It was raised at a UKHCDO meeting that Immuno would start selling Kryobulin Factor 8 concentrate at two prices.

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Professor Ingram asked Professor Charles Rizza to update the UKHCDO meeting minutes regarding the Immuno products.

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Immuno considered that the British market would accept a higher risk of hepatitis for a lower-priced product.

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An article in The Lancet expressed concerns about the long-term consequences of non-A non-B Hepatitis.

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Professor Zuckerman concluded that the use of blood concentrates should be restricted to life-threatening situations until blood donors could be screened for non-A non-B Hepatitis.

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Armour Pharmaceutical published information about the current state of knowledge regarding non-A non-B Hepatitis.

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An article was published which assessed the severity of liver disease in people with haemophilia.

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It was estimated that Hepatitis C first emerged over 3,000 years ago.

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Professor Arthur Bloom wrote to a GP to say that a small percentage of freeze-dried preparations contained the virus of serum hepatitis and therefore were potentially dangerous.

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There were a number of reports that non-A non-B Hepatitis was linked to persistent liver damage.

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The hepatitis risk of commercial blood was markedly higher than that of blood from unpaid donors.

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In a paper by Dr Rosemary Biggs, it was noted that of 1,800 patients whose cases occurred between 1969 and 1971, 302 had been tested by a range of different tests for the presence of the Australia antigen.

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By the mid 1970s a number of doctors held the view that non-A non-B Hepatitis was a mild or benign disease, which rested centrally on assertion and/or wishful thinking rather than evidence.

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The publication of "Percutaneous Liver Biopsy and Chronic Liver Disease in Haemophiliacs" in The Lancet meant that clinicians could no longer rely on the absence of overt or acute signs of hepatitis as a reliable indicator that non-A non-B Hepatitis would not develop.

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The results of a study of 31 patients at the Royal Free Hospital treated for the first time with concentrate indicated an approaching 100% "attack rate" of hepatitis infection whichever of NHS or commercial concentrate was used, due to the sheer size of the pools.

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In "Liver function in Edinburgh haemophiliacs: a five-year follow-up", a comparison of test results before the introduction of NHS concentrates in 1974 with test results from 1979 showed that the liver function of those treated with Factor 8 concentrate had deteriorated whereas those treated with cryoprecipitate had not.

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